Myosin Light Chain 2 (MYL2) Mouse Monoclonal Antibody [Clone ID: 7C9]

Specifications

Product Data
Clone Name	7C9
Applications	WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500-1/2000.  Immunohistochemistry on Paraffin Sections: 1/100.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of MYL2 expressed in E. Coli.
Specificity	Recognizes Human Myosin light chain 2 (MYL2).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	myosin light chain 2
Database Link	Entrez Gene 4633 Human UniProt ID P10916
Background	MYL2 (Myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Synonyms	MLC-2v, MLC-2
Reference Data

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