AKT3 Mouse Monoclonal Antibody [Clone ID: 3B12F3F10]

Specifications

Product Data
Clone Name	3B12F3F10
Applications	ELISA, WB
Recommend Dilution	ELISA:  1/10000.  Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Akt3 expressed in E. Coli.
Specificity	Recognizes Akt3
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	AKT serine/threonine kinase 3
Database Link	Entrez Gene 10000 Human UniProt ID Q9Y243
Background	Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3), with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Synonyms	RAC-PK-gamma, Protein kinase B gamma, PKBG, STK-2
Reference Data

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