Eph receptor B4 (EPHB4) Mouse Monoclonal Antibody [Clone ID: 5B8F7]

CAT#: AM06124SU-N

Eph receptor B4 (EPHB4) mouse monoclonal antibody, clone 5B8F7, Ascites



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CNY 3,432.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name 5B8F7
Applications ELISA, IHC, WB
Recommend Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of EphB4 expressed in E. Coli.
Specificity Recognizes EPH receptor B4 (EphB4)
Formulation State: Ascites
State: Ascitic fluid
Preservative: 0.03% Sodium Azide
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name EPH receptor B4
Background EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy.
Synonyms Ephrin type-B receptor 4, HTK, TYRO11
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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