EHMT1/GLP (EHMT1) Mouse Monoclonal Antibody [Clone ID: 1B7B4]

Specifications

Product Data
Clone Name	1B7B4
Applications	ELISA, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of GLP expressed in E. Coli.
Specificity	This antibody reacts to GLP.
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0,03% sodium azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	euchromatic histone lysine methyltransferase 1
Database Link	Entrez Gene 79813 Human UniProt ID Q9H9B1
Background	Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
Synonyms	EUHMTASE1, GLP, KIAA1876, KMT1D, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5
Reference Data

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