KDM1A Mouse Monoclonal Antibody [Clone ID: 1B2E5]

Specifications

Product Data
Clone Name	1B2E5
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. ELISA: 1/10000. Immunohistochemistry on Paraffin Sections: 1/200- 1/1000.
Reactivity	Human, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human LSD1 expressed in E. Coli.
Specificity	This antibody reacts to LSD1/AOF2.
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	93 kDa
Gene Name	lysine demethylase 1A
Database Link	Entrez Gene 23028 Human UniProt ID O60341
Background	The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Synonyms	Lysine-specific histone demethylase 1, KIAA0601, LSD1
Reference Data

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