AMH Mouse Monoclonal Antibody [Clone ID: 5/6]

Specifications

Product Data
Clone Name	5/6
Applications	IHC, WB
Recommend Dilution	Western blot. Immunohistology on Paraffin Sections: 1/20-1/40 (Requires antigen retrieval using heat treatment methods prior to staining, Sodium Citrate buffer pH 6.0 is recommended for this purpose). Recommended Positive Control: Ovary Tissue.
Reactivity	Human, Monkey, Mouse, Sheep
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide derived from Human AMH. Spleen cells from immunised T/O outbred mice were fused with cells of the SP2/0 myeloma cell line
Specificity	This antibody clone 5/6 is specific for Human anti-Mullerian Hormone (AMH), originally classified as a foetal testicular hormone that inhibits Mullerian duct development. AMH is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer.
Isotype	IgG1
Formulation	State: Supernatant State: Liquid Concentrated Tissue Culture Supernatant Preservative: 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	anti-Mullerian hormone
Database Link	Entrez Gene 268 Human UniProt ID P03971
Background	Anti Mullerian Hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
Synonyms	Muellerian-inhibiting factor, MIF, MIS
Reference Data

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