BNP (NPPB) (NT-proBNP 13-27) Mouse Monoclonal Antibody [Clone ID: 18H5]

Specifications

Product Data
Clone Name	18H5
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blotting: Detects a band of approximately 9kDa when using recombinant NT-proBNP. Immunoassay.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Amino acids 13-27 of NT-proBNP
Specificity	This antibody detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP.
Isotype	IgG1
Formulation	Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide (NaN3) State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	natriuretic peptide B
Database Link	Entrez Gene 4879 Human UniProt ID P16860
Background	NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.
Synonyms	NPPB, Brain natriuretic peptide, BNP, proBNP
Reference Data

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