Folate Binding Protein (FOLR1) Mouse Monoclonal Antibody [Clone ID: SF55 (BGN/1210/55)]

Specifications

Product Data
Clone Name	SF55 (BGN/1210/55)
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Bovine, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Folate binding protein from Bovine milk.
Specificity	This antibody reacts with Folate Binding Protein (FBP) a 30 kDa protein with a high affinity for folate and several reduced folic acid derivatives, that mediates the intracelullar delivery of 5-Methyl-Tetrahydrofolate. Membrane bound and soluble forms of a high affinity FBP have been found in kidney, placenta, serum, milk, and several cell lines.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	folate receptor 1 (adult)
Database Link	Entrez Gene 2348 Human UniProt ID P15328
Background	Folate Binding Protein, has a high affinity for folic acid and for several reduced folic acid derivatives and mediates delivery of 5 methyltetrahydrofolate to the interior of cells. Membrane bound and soluble forms of a high affinity folate binding protein have been found in kidney, placenta, serum, milk, and in several cell lines. The 2 forms have similar binding characteristics for folates, are immunologically crossreactive, and, based upon limited amino acid sequence data, are nearly identical. There may be a precursor product relationship between the membrane and soluble forms, the membrane form having additional amino acid residues and greater molecular weight. The membrane form has been shown to mediate the transport of folate in cells grown in physiologic concentrations of folate. A function for the soluble form, which is found in serum, milk, and urine, has not been identified.
Synonyms	FR-alpha, Folate receptor 1, MOv18, KB cells FBP, FOLR1, FOLR
Reference Data

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