NELFE Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) I4-F380
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of 500mM PBS, 300mM NaCl, 10%Glycerol, pH7.4
Note	MADE TO ORDER | Recombinant Human NELF-E is produced by E.coli expression system and the target gene encoding I4-F380 is expressed with a His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	7936
UniProt ID	P18615
Summary	Negative elongation factor complex member E is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.