Cxcl1 (NM_008176) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Mouse CXCL1, the region of Asn29-Lys96, from gene Accession# NM_008176.3
Tag	Tag Free
Predicted MW	7.4 kDa
Concentration	lot specific
Purity	>98%, as determined by Coomassie stained SDS-PAGE.
Buffer	1 x PBS
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	Recombinant mouse CXCL1 (KC) chemoattracts Baf3-mCXCR2 transfectants in a dose-dependent manner. The ED50 for this effect is 0.1– 0.6 ng/mL.
Endotoxin	Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_032202
Locus ID	14825
UniProt ID	P12850, A2RTH0
Refseq Size	964
Cytogenetics	5 44.78 cM
Refseq ORF	288
Synonyms	F; Fsp; Gr; gro; Gro1; KC; Mg; Mgsa; N5; N51; Scyb; Scyb1
Summary	This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.