Annexin A2 / ANXA2 (1-339, His-tag) Human Protein
CAT#: AR09353PU-L
Annexin A2 / ANXA2 (1-339, His-tag) human recombinant protein, 0.5 mg
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CNY 13,720.00
货期*
详询
规格
Cited in 7 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMST VHEILCKLSL EGDHSTPPSA YGSVKAYTNF DAERDALNIE TAIKTKGVDE VTIVNILTNR SNAQRQDIAF AYQRRTKKEL ASALKSALSG HLETVILGLL KTPAQYDASE LKASMKGLGT DEDSLIEIIC SRTNQELQEI NRVYKEMYKT DLEKDIISDT SGDFRKLMVA LAKGRRAEDG SVIDYELIDQ DARDLYDAGV KRKGTDVPKW ISIMTERSVP HLQKVFDRYK SYSPYDMLES IRKEVKGDLE NAFLNLVQCI QNKPLYFADR LYDSMKGKGT RDKVLIRIMV SRSEVDMLKI RSEFKRKYGK SLYYYIQQDT KGDYQKALLY LCGGDD
|
Tag | His-tag |
Predicted MW | 42.8 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1 M NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant Annexin A2 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001002857 |
Locus ID | 302 |
UniProt ID | P07355, A0A024R5Z7 |
Cytogenetics | 15q22.2 |
Synonyms | ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV |
Summary | This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019] |
Protein Families | Druggable Genome, Secreted Protein, Stem cell - Pluripotency |
Citations (7)
The use of this Proteins has been cited in the following citations: |
---|
A monoclonal antibody against annexin A2 targets stem and progenitor cell fractions in tumors
,null,
Translational Oncology
,PubMed ID 34715620
[ANXA2]
|
Clinical Significance of Annexin A2 Expression in Breast Cancer Patients
,null,
Cancers
,PubMed ID 33374917
[ANXA2]
|
Recombinant annexin A6 promotes membrane repair and protects against muscle injury
,null,
The Journal of Clinical Investigation
,PubMed ID 31545299
[ANXA2]
|
Annexin A2 contributes to cisplatin resistance by activation of JNK-p53 pathway in non-small cell lung cancer cells
,null,
Journal of Experimental & Clinical Cancer Research : CR
,PubMed ID 28886730
[ANXA2]
|
An actin-dependent annexin complex mediates plasma membrane repair in muscle
,null,
The Journal of Cell Biology
,PubMed ID 27298325
[ANXA2]
|
Annexin A2 Enhances Complement Activation by Inhibiting Factor H
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 26729803
[ANXA2]
|
Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans *
,null,
Molecular & Cellular Proteomics : MCP
,PubMed ID 21817168
[ANXA2]
|
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