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Trpa1 (NM_207608) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR203182L3V
- LentiORF®
-
Lenti ORF particles, Trpa1 (Myc-DDK-tagged ORF) - Rat transient receptor potential cation channel, subfamily A, member 1 (Trpa1), 200ul, >10^7 TU/mL
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CNY 19,846.00
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Trpa1 (NM_207608) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Anktm1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_207608 |
| ORF Size | 3375 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR203182).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_207608.1 |
| RefSeq Size | 3378 bp |
| RefSeq ORF | 3378 bp |
| Locus ID | 312896 |
| Gene Summary | Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:14712238). Is also activated by menthol (in vitro) (By similarity). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Pinosylvin Inhibits TRPA1-Induced Calcium Influx In Vitro and TRPA1-Mediated Acute Paw Inflammation In Vivo.
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Basic & clinical pharmacology & toxicology
,PubMed ID 26335783
[Trpa1]
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