TRABD2B (NM_001194986) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC231288L1V
- LentiORF®
Lenti ORF particles, TRABD2B (Myc-DDK tagged) - Human UPF0632 protein A (LOC388630), 200ul, >10^7 TU/mL
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CNY 9,690.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | TRABD2B (NM_001194986) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | TIKI2 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_001194986 |
ORF Size | 1551 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC231288).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001194986.1 |
RefSeq ORF | 1554 bp |
Locus ID | 388630 |
MW | 57.9 kDa |
Gene Summary | Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4 + T cells by degrading viral Gag polyprotein.
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Nature immunology
,PubMed ID 31061530
[TRABD2B]
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