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Ephexin 1 (NGEF) (NM_001114090) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC226027L3V
- LentiORF®
-
Lenti ORF particles, NGEF (Myc-DDK-tagged)-Human neuronal guanine nucleotide exchange factor (NGEF), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,830.00
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规格
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Specifications
| Product Data | |
| Product Name | Ephexin 1 (NGEF) (NM_001114090) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ARHGEF27; EPHEXIN |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001114090 |
| ORF Size | 1854 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC226027).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001114090.1 |
| RefSeq ORF | 1857 bp |
| Locus ID | 25791 |
| Protein Pathways | Axon guidance |
| MW | 71.2 kDa |
| Gene Summary | Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).[UniProtKB/Swiss-Prot Function] |
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