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SGLT2 (SLC5A2) (NM_003041) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC224822L1V
- LentiORF®
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Lenti ORF particles, SLC5A2 (Myc-DDK tagged) - Human solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2), 200ul, >10^7 TU/mL
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CNY 13,015.00
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规格
| Cited in 5 publications. |
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经常一起买 (3)
热销推荐Specifications
| Product Data | |
| Product Name | SGLT2 (SLC5A2) (NM_003041) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | SGLT2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_003041 |
| ORF Size | 2016 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC224822).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_003041.2 |
| RefSeq Size | 2271 bp |
| RefSeq ORF | 2019 bp |
| Locus ID | 6524 |
| Protein Families | Transmembrane |
| MW | 72.7 kDa |
| Gene Summary | This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
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Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors
,Sipos, ?;Szennyes, E;Hajnal, N?;Kun, S;Szab?, KE;Uray, K;Soms?k, L;Docsa, T;Bokor, ?;,
Pharmaceuticals (Basel, Switzerland) 2021
,PubMed ID 33920838
[SLC5A2]
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Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo
,null,
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
,PubMed ID 30627010
[SLC5A2]
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SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models
,null,
Acta Pharmacologica Sinica
,PubMed ID 24786232
[SLC5A2]
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Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models.
,null,
The Journal of pharmacology and experimental therapeutics
,PubMed ID 18583547
[SLC5A2]
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Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level.
,null,
The Journal of pharmacology and experimental therapeutics
,PubMed ID 17050778
[SLC5A2]
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