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MDM2 (NM_002392) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC219518L1V
- LentiORF®
-
Lenti ORF particles, MDM2 (Myc-DDK tagged) - Human Mdm2 p53 binding protein homolog (mouse) (MDM2), transcript variant MDM2, 200ul, >10^7 TU/mL
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CNY 9,500.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | MDM2 (NM_002392) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ACTFS; hdm2; HDMX; LSKB |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_002392 |
| ORF Size | 1491 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC219518).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_002392.2 |
| RefSeq Size | 2357 bp |
| RefSeq ORF | 1494 bp |
| Locus ID | 4193 |
| Domains | zf-RanBP, MDM2 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Bladder cancer, Cell cycle, Chronic myeloid leukemia, Endocytosis, Glioma, Melanoma, p53 signaling pathway, Pathways in cancer, Prostate cancer, Ubiquitin mediated proteolysis |
| MW | 55.8 kDa |
| Gene Summary | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
