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Frizzled 4 (FZD4) (NM_012193) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC217286L1V
- LentiORF®
-
Lenti ORF particles, FZD4 (Myc-DDK tagged) - Human frizzled family receptor 4 (FZD4), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Frizzled 4 (FZD4) (NM_012193) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_012193 |
| ORF Size | 1611 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC217286).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_012193.2 |
| RefSeq Size | 7394 bp |
| RefSeq ORF | 1614 bp |
| Locus ID | 8322 |
| Domains | FRI, Frizzled |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| MW | 60.3 kDa |
| Gene Summary | This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families.
,null,
Clinical experimental ophthalmology
,PubMed ID 31765079
[FZD4]
|
|
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
,null,
Developmental Cell
,PubMed ID 25584796
[FZD4]
|
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