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Claudin18 (CLDN18) (NM_016369) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC212135L4V
- LentiORF®
-
Lenti ORF particles, CLDN18 (mGFP-tagged)-Human claudin 18 (CLDN18), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Claudin18.2(CLDN18.2) Rabbit monoclonal antibody,clone OTIR56A8
CNY 3,600.00
Specifications
| Product Data | |
| Product Name | Claudin18 (CLDN18) (NM_016369) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | SFTA5; SFTPJ |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_016369 |
| ORF Size | 783 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC212135).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016369.3 |
| RefSeq Size | 3359 bp |
| RefSeq ORF | 786 bp |
| Locus ID | 51208 |
| Domains | PMP22_Claudin |
| Protein Families | Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| MW | 27.7 kDa |
| Gene Summary | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] |
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