Manic Fringe (MFNG) (NM_002405) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211955L4V

  • LentiORF®

Lenti ORF particles, MFNG (mGFP-tagged) - Human MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,120.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Manic Fringe (MFNG) (NM_002405) Human Tagged ORF Clone Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_002405
ORF Size 963 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC211955).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_002405.2
RefSeq Size 2040 bp
RefSeq ORF 966 bp
Locus ID 4242
Domains Fringe
Protein Families Druggable Genome
Protein Pathways Notch signaling pathway
MW 36 kDa
Gene Summary This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the LFNG (GeneID: 3955) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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