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HDAC6 (NM_006044) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209649L4V
- LentiORF®
-
Lenti ORF particles, HDAC6 (mGFP-tagged) - Human histone deacetylase 6 (HDAC6), 200ul, >10^7 TU/mL
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CNY 12,540.00
货期*
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规格
| Cited in 1 publication. |
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经常一起买 (3)
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Specifications
| Product Data | |
| Product Name | HDAC6 (NM_006044) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CPBHM; HD6; JM21; PPP1R90 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_006044 |
| ORF Size | 3645 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209649).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006044.2 |
| RefSeq Size | 4099 bp |
| RefSeq ORF | 3648 bp |
| Locus ID | 10013 |
| Domains | Hist_deacetyl, zf-UBP |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 131.2 kDa |
| Gene Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity
,Carew, JS;Espitia, CM;Zhao, W;Visconte, V;Anwer, F;Kelly, KR;Nawrocki, ST;,
Blood Adv
,PubMed ID 31015208
[HDAC6]
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