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Eph receptor B4 (EPHB4) (NM_004444) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208559L1V
- LentiORF®
-
Lenti ORF particles, EPHB4 (Myc-DDK tagged) - Human EPH receptor B4 (EPHB4), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Eph receptor B4 (EPHB4) (NM_004444) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CMAVM2; HFASD; HTK; LMPHM7; MYK1; TYRO11 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_004444 |
| ORF Size | 2961 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208559).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004444.4 |
| RefSeq Size | 4369 bp |
| RefSeq ORF | 2964 bp |
| Locus ID | 2050 |
| Domains | pkinase, EPH_lbd, TyrKc, SAM, S_TKc, FN3 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Axon guidance |
| MW | 108.27 kDa |
| Gene Summary | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells
,null,
JCI Insight
,PubMed ID 35015735
[EPHB4]
|
|
The EphB4 Receptor Tyrosine Kinase Promotes Lung Cancer Growth: A Potential Novel Therapeutic Target
,null,
PLoS ONE
,PubMed ID 23844053
[EPHB4]
|
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