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CBX6 (NM_014292) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204166L1V
- LentiORF®
-
Lenti ORF particles, CBX6 (Myc-DDK tagged) - Human chromobox homolog 6 (CBX6), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | CBX6 (NM_014292) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_014292 |
| ORF Size | 1236 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204166).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014292.3 |
| RefSeq Size | 3284 bp |
| RefSeq ORF | 1239 bp |
| Locus ID | 23466 |
| Protein Families | Transcription Factors |
| MW | 43.9 kDa |
| Gene Summary | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer
,null,
Scientific Reports
,PubMed ID 30655550
[CBX6]
|
|
Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme
,null,
PLoS ONE
,PubMed ID 24260522
[CBX6]
|
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