Rad51b (NM_009014) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR220772L4V

  • LentiORF®

Lenti ORF particles, Rad51b (GFP-tagged) - Mouse RAD51-like 1 (S. cerevisiae) (Rad51l1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Rad51b (NM_009014) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms AI553500; mREC2; R51H2; Rad51l1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_009014
ORF Size 1050 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR220772).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_009014.3, NP_033040.2
RefSeq Size 1858 bp
RefSeq ORF 1053 bp
Locus ID 19363
Gene Summary Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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