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Puf60 (NM_028364) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR218047L4V
- LentiORF®
-
Lenti ORF particles, Puf60 (GFP-tagged) - Mouse poly-U binding splicing factor 60 (Puf60), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,495.00
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Specifications
| Product Data | |
| Product Name | Puf60 (NM_028364) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2410104I19Rik; 2810454F19Rik; SIAHBP1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_028364 |
| ORF Size | 1692 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR218047).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_028364.2, NP_082640.2 |
| RefSeq Size | 1929 bp |
| RefSeq ORF | 1695 bp |
| Locus ID | 67959 |
| Gene Summary | DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice site and pyrimidine tract in a cooperative manner with U2AF2. Involved in apoptosis induction when overexpressed in HeLa cells. Modulates alternative splicing of several mRNAs. Binds to relaxed DNA of active promoter regions. Binds to the pyrimidine tract and 3'-splice site regions of pre-mRNA; binding is enhanced in presence of U2AF2. Binds to Y5 RNA in association with TROVE2. Binds to poly(U) RNA (By similarity).[UniProtKB/Swiss-Prot Function] |
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