TOR1AIP2 (NM_001199260) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	IFRG15; LULL1; NET9
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331281 representing NM_001199260. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCCGACAGTGGACTTAGGGAACCTCAAGAGGACTCTCAAAAGGATTTGGAAAATGATCCATCAGTA AATTCTCAGGCGCAGGAGACCACAATCATAGCAAGTAATGCTGAAGAAGCTGAGATCCTACACTCTGCC TGTGGTCTTAGCAAAGACCACCAAGAGGTAGAGACAGAAGGTCCAGAAAGTGCAGATACAGGTGATAAA TCAGAAAGTCCAGATGAAGCAAATGTGGGGAAACATCCAAAGGATAAAACAGAAGATGAGAACAAGCAG AGTTTTCTGGATGGCGGAAAAGGGCATCACCTCCCTTCAGAAAATCTGGGTAAAGAACCCTTGGATCCA GATCCCAGCCATTCTCCAAGTGACAAGGTAGGAAGAGCAGATGCACACTTAGGGAGCAGCTCTGTGGCC CTCCCTAAGGAAGCGAGTGACGGAACTGGAGCATCTCAGGAACCACCTACTACAGACTCCCAGGAGGCC CAGAGTCCTGGTCATTCCAGTGCAGGGCAAGAGGGTGAGGATACACTGAGGAGGCGACTGCTGGCCCCA GAGGCTGGAAGTCATCCACAACAAACACAAAAATTGGAAGAAATTAAAGAGAATGCACAGGACACCATG AGACAGATTAATAAAAAGGGTTTTTGGAGCTATGGCCCTGTGATTCTTGTCGTCCTGGTTGTGGCTGTT GTGGCAAGTTCTGTGAATAGCTACTATTCCTCTCCAGCCCAGCAAGTGCCCAAAAATCCAGCTTTGGAG GCCTTTTTGGCCCAGTTTAGCCAATTGGAAGATAAATTTCCAGGCCAGAGTTCCTTCCTGTGGCAGAGA GGACGGAAGTTTCTCCAGAAGCACCTCAATGCTTCCAACCCCACTGAGCCAGCCACCATCATATTTACA GCAGCTCGGGAGGGAAGAGAGACCCTGAAGTGCCTGAGCCACCATGTTGCAGATGCCTACACCTCTTCC CAGAAAGTCTCTCCCATTCAGATTGATGGGGCTGGAAGGACCTGGCAGGACAGTGACACGGTCAAGCTG TTGGTTGACCTGGAGCTGAGCTATGGGTTTGAGAATGGCCAGAAGGCTGCTGTGGTACACCACTTCGAA TCCTTCCCTGCCGGCTCCACTTTGATCTTCTATAAGTATTGTGATCATGAGAATGCTGCCTTTAAAGAT GTGGCCCTGGTCCTGACTGTTCTGCTAGAGGAGGAAACATTAGAAGCAAGTGTAGGCCCAAGGGAAACG GAAGAAAAAGTGAGAGACTTACTCTGGGCCAAGTTTACCAACTCTGACACTCCCACCTCCTTCAACCAC ATGGACTCAGACAAATTGAGTGGGCTGTGGAGCCGAATTTCACACCTGGTACTGCCAGTCCAGCCAGTG AGTAGCATAGAAGAACAGGGGTGCCTTTTCTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001199260
Insert Size	1413 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001199260.1
RefSeq Size	8331 bp
RefSeq ORF	1413 bp
Locus ID	163590
UniProt ID	Q8NFQ8
Protein Families	Transmembrane
MW	51.3 kDa
Gene Summary	One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (3) contains the same 5' non-coding exons, but has a completely different set of coding exons compared to variant 1. This results in a longer isoform b (torsin-1A-interacting protein 2) distinct from isoform a, referred to as interferon alpha responsive protein.

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