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Macrophage Scavenger Receptor I (MSR1) (NM_138716) Human Untagged Clone
CAT＃: SC127877
MSR1 (untagged)-Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII
CNY 3,656.00
CNY 6,270.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD204; phSR1; phSR2; SCARA1; SR-A; SR-AI; SR-AII; SR-AIII; SRA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_138716, the custom clone sequence may differ by one or more nucleotides
ATGGAGCAGTGGGATCACTTTCACAATCAACAGGAGGACACTGATAGCTGCTCCGAATCTGTGAAATTTG ATGCTCGCTCAATGACAGCTTTGCTTCCTCCGAATCCTAAAAACAGCCCTTCCCTTCAAGAGAAACTGAA GTCCTTCAAAGCTGCACTGATTGCCCTTTACCTCCTCGTGTTTGCAGTTCTCATCCCTCTCATTGGAATA GTGGCAGCTCAACTCCTGAAGTGGGAAACGAAGAATTGCTCAGTTAGTTCAACTAATGCAAATGATATAA CTCAAAGTCTCACGGGAAAAGGAAATGACAGCGAAGAGGAAATGAGATTTCAAGAAGTCTTTATGGAACA CATGAGCAACATGGAGAAGAGAATCCAGCATATTTTAGACATGGAAGCCAACCTCATGGACACAGAGCAT TTCCAAAATTTCAGCATGACAACTGATCAAAGATTTAATGACATTCTTCTGCAGCTAAGTACCTTGTTTT CCTCAGTCCAGGGACATGGGAATGCAATAGATGAAATCTCCAAGTCCTTAATAAGTTTGAATACCACATT GCTTGATTTGCAGCTCAACATAGAAAATCTGAATGGCAAAATCCAAGAGAATACCTTCAAACAACAAGAG GAAATCAGTAAATTAGAGGAGCGTGTTTACAATGTATCAGCAGAAATTATGGCTATGAAAGAAGAACAAG TGCATTTGGAACAGGAAATAAAAGGAGAAGTGAAAGTACTGAATAACATCACTAATGATCTCAGACTGAA AGATTGGGAACATTCTCAGACCTTGAGAAATATCACTTTAATTCAAGGTCCTCCTGGACCCCCGGGTGAA AAAGGAGATCGAGGTCCCACTGGAGAAAGTGGTCCACGAGGATTTCCAGGTCCAATAGGTCCTCCGGGTC TTAAAGGTGATCGGGGAGCAATTGGCTTTCCTGGAAGTCGAGGACTCCCAGGATATGCCGGAAGGCCAGG AAATTCTGGACCAAAAGGCCAGAAAGGGGAAAAGGGGAGTGGAAACACATTAAGTACTGGTCCAATATGG CTGAATGAAGTGTTTTGTTTTGGGAGAGAATCATCTATTGAAGAATGTAAAATTCGGCAATGGGGGACAA GAGCCTGTTCACATTCTGAAGATGCTGGAGTCACTTGCACTTTATAA >OriGene 5' read for NM_138716 unedited
AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGATTTCCTTTCTTCATGTACC AGATGCTGAAATACTATGAGATAAAGATTTTAGGTTTCAATTGTAAAGAGAGAGAAGTGG ATAAATCAGTGCTGCTTTCTTTAGGACGAAAGAAGTATGGAGCAGTGGGATCACTTTCAC AATCAACAGGAGGACACTGATAGCTGCTCCGAATCTGTGAAATTTGATGCTCGCTCAATG ACAGCTTTGCTTCCTCCGAATCCTAAAAACAGCCCTTCCCTTCAAGAGAAACTGAAGTCC TTCAAAGCTGCACTGATTGCCCTTTACCTCCTCGTGTTTGCAGTTCTCATCCCTCTCATT GGAATAGTGGCAGCTCAACTCCTGAAGTGGGAAACGAAGAATTGCTCAGTTAGTTCAACT AATGCAAATGATATAACTCANAGTCTCACGGGAAAAGGAAATGACAGCGAAGAGGAAATG AGATTTCAAGAAGTCTTTATGGAACACATGAGCAACATGGAGAAGAGAATCCAGCATATT TTAGACATGGAAGCCCACCTCATGGACACAGAGCATTTNCAANANTCAGCATGACACTGA TCAAGATTTATGACATTCTCTGCACTAATACCTGTTTCTCATCAGGACATGGATGCATAA TGAAATCTCAGTCTATAGTTGATACAATGCTGATGAGCTACTAAAACT |
| Restriction Sites | Please inquire |
| ACCN | NM_138716 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_138716.1, NP_619730.1 |
| RefSeq Size | 3493 bp |
| RefSeq ORF | 1167 bp |
| Locus ID | 4481 |
| UniProt ID | P21757 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (SR-AIII) lacks an exon in the coding region, but maintains the same reading frame, as compared to variant SR-AI. It encodes an isoform type 3 that lacks 63 internal amino acids compared to isoform type 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223314 | MSR1 (Myc-DDK-tagged)-Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII |
CNY 3,656.00 |
|
| RC223314L3 | Lenti ORF clone of Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223314L4 | Lenti ORF clone of Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII, mGFP tagged |
CNY 5,890.00 |
|
| RG223314 | MSR1 (tGFP-tagged) - Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII |
CNY 4,370.00 |
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