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RTEL1 (NM_001283010) Human Tagged ORF Clone
CAT＃: RG239863
- TrueORF®
RTEL1 (tGFP-tagged) - Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 4
ORF Plasmid: DDK
"NM_001283010" in other vectors (2)
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CNY 10,360.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239863 representing NM_001283010.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCGTACAATTACTTGTTGGATGCCAAGAGCCGCAGAGCACACAACATTGACCTGAAGGGGACAGTC GTGATCTTTGACGAAGCTCACAACGTGGAGAAGATGTGTGAAGAATCGGCATCCTTTGACCTGACTCCC CATGACCTGGCTTCAGGACTGGACGTCATAGACCAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAG GGTGAGCCCCACCCGGAGTTCAGCGCGGACTCCCCCAGCCCAGGGCTGAACATGGAGCTGGAAGACATT GCAAAGCTGAAGATGATCCTGCTGCGCCTGGAGGGGGCCATCGATGCTGTTGAGCTGCCTGGAGACGAC AGCGGTGTCACCAAGCCAGGGAGCTACATCTTTGAGCTGTTTGCTGAAGCCCAGATCACGTTTCAGACC AAGGGCTGCATCCTGGACTCGCTGGACCAGATCATCCAGCACCTGGCAGGACGTGCTGGAGTGTTCACC AACACGGCCGGACTGCAGAAGCTGGCGGACATTATCCAGATTGTGTTCAGTGTGGACCCCTCCGAGGGC AGCCCTGGTTCCCCAGCAGGGCTGGGGGCCTTACAGTCCTATAAGGTGCACATCCATCCTGATGCTGGT CACCGGAGGACGGCTCAGCGGTCTGATGCCTGGAGCACCACTGCAGCCAGAAAGCGAGGGAAGGTGCTG AGCTACTGGTGCTTCAGTCCCGGCCACAGCATGCACGAGCTGGTCCGCCAGGGCGTCCGCTCCCTCATC CTTACCAGCGGCACGCTGGCCCCGGTGTCCTCCTTTGCTCTGGAGATGCAGATCCCTTTCCCAGTCTGC CTGGAGAACCCACACATCATCGACAAGCACCAGATCTGGGTGGGGGTCGTCCCCAGAGGCCCCGATGGA GCCCAGTTGAGCTCCGCGTTTGACAGACGGTTTTCCGAGGAGTGCTTATCCTCCCTGGGGAAGGCTCTG GGCAACATCGCCCGCGTGGTGCCCTATGGGCTCCTGATCTTCTTCCCTTCCTATCCTGTCATGGAGAAG AGCCTGGAGTTCTGGCGGGCCCGCGACTTGGCCAGGAAGATGGAGGCGCTGAAGCCGCTGTTTGTGGAG CCCAGGAGCAAAGGCAGCTTCTCCGAGACCATCAGTGCTTACTATGCAAGGGTTGCCGCCCCTGGGTCC ACCGGCGCCACCTTCCTGGCGGTCTGCCGGGGCAAGGCCAGCGAGGGGCTGGACTTCTCAGACACGAAT GGCCGTGGTGTGATTGTCACGGGCCTCCCGTACCCCCCACGCATGGACCCCCGGGTTGTCCTCAAGATG CAGTTCCTGGATGAGATGAAGGGCCAGGGTGGGGCTGGGGGCCAGTTCCTCTCTGGGCAGGAGTGGTAC CGGCAGCAGGCGTCCAGGGCTGTGAACCAGGCCATCGGGCGAGTGATCCGGCACCGCCAGGACTACGGA GCTGTCTTCCTCTGTGACCACAGGTTCGCCTTTGCCGACGCAAGAGCCCAACTGCCCTCCTGGGTGCGT CCCCACGTCAGGGTGTATGACAACTTTGGCCATGTCATCCGAGACGTGGCCCAGTTCTTCCGTGTTGCC GAGCGAACTATGCCAGCGCCGGCCCCCCGGGCTACAGCACCCAGTGTGCGTGGAGAAGATGCTGTCAGC GAGGCCAAGTCGCCTGGCCCCTTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACCTGCATGTCCCCAGC CTGAAGCAGAGGTCCTCAGGGTCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTGTGTGGAGTATGAG CAGGAGCCAGTTCCTGCCCGGCAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCACAGCGAACAGCGG GCGGGGAGCCCTGGCGAGGAGCAGGCCCACAGCTGCTCCACCCTGTCCCTCCTGTCTGAGAAGAGGCCG GCAGAAGAACCGCGAGGAGGGAGGAAGAAGATCCGGCTGGTCAGCCACCCGGAGGAGCCCGTGGCTGGT GCACAGACGGACAGGGCCAAGCTCTTCATGGTGGCCGTGAAGCAGGAGTTGAGCCAAGCCAACTTTGCC ACCTTCACCCAGGCCCTGCAGGACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCTGTCTCGGC CCCCTCTTTGCTGAGGACCCCAAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCGGCCCCAC CATAAGCAGCAGTTTGAGGAGGTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCTGAGCAC AGCATTCCCCGAAGGCAGCGGGCACAGCCGGTCCTGGACCCCACTGGAAGAACGGCGCCGGATCCCAAG CTGACCGTGTCCACGGCTGCAGCCCAGCAGCTGGACCCCCAAGAGCACCTGAACCAGGGCAGGCCCCAC CTGTCGCCCAGGCCACCCCCAACAGGAGACCCTGGCAGCCAACCACAGTGGGGGTCTGGAGTGCCCAGA GCAGGGAAGCAGGGCCAGCACGCCGTGAGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCGCG GGCTGTAGCCAACTCTTGGCAGCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGCT GTGTTGGCCGCCCTGACCACTGCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTG CGTCCACACCACAAGCAGCGCTTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTACCCGGGCATG GAGCCACCGGGACCCCAGGAGGAGAGGCTTGCCGTGCCTCCTGTGCTTACCCACAGGGCTCCCCAACCA GGCCCCTCACGGTCCGAGAAGACCGGGAAGACCCAGAGCAAGATCTCGTCCTTCCTTAGACAGAGGCCA GCAGGGACTGTGGGGGCGGGCGGTGAGGATGCAGGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCT GCAGCATCTGAGTGGGGCCTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239863
Blue=ORF Red=Cloning site Green=Tag(s) MPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQ GEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQT KGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAG HRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVC LENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEK SLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTN GRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYG AVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVS EAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQR AGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFA TFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEH SIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPR AGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFV RPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRP AGTVGAGGEDAGPSQSSGPPHGPAASEWGL TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001283010 |
| ORF Size | 2988 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001283010.1, NP_001269939.1 |
| RefSeq Size | 4691 bp |
| RefSeq ORF | 2991 bp |
| Locus ID | 51750 |
| UniProt ID | Q9NZ71 |
| Protein Families | Druggable Genome |
| MW | 108.9 kDa |
| Gene Summary | This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] |
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