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Capicua (CIC) (NM_015125) Human Tagged ORF Clone
CAT＃: RG215209
- TrueORF®
CIC (tGFP-tagged) - Human capicua homolog (Drosophila) (CIC)
ORF Plasmid: DDK
"NM_015125" in other vectors (6)
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CNY 17,670.00
Product images
CNY 1,000.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | MRD45 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG215209 representing NM_015125
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTATTCGGCCCACAGGCCCCTGATGCCCGCGTCCAGCGCGGCCTCCCGTGGCCTCGGCATGTTCGTGT GGACGAATGTGGAACCTCGCTCTGTGGCTGTGTTCCCTTGGCACTCCTTAGTCCCCTTCCTGGCACCCAG CCAGCCTGACCCCTCCGTGCAGCCGAGCGAGGCCCAGCAACCTGCCAGCCACCCAGTGGCCTCCAACCAG AGCAAAGAACCTGCTGAGTCGGCAGCTGTTGCTCATGAACGGCCACCAGGTGGGACAGGGAGTGCTGACC CTGAGCGGCCCCCTGGAGCCACATGCCCTGAGAGCCCAGGACCCGGACCCCCACACCCTTTGGGGGTGGT GGAATCTGGTAAGGGTCCGCCTCCCACCACGGAGGAGGAGGCCTCCGGCCCCCCAGGAGAGCCCCGGCTG GACAGTGAGACAGAGAGTGACCATGATGATGCCTTCCTCTCCATCATGTCTCCTGAGATCCAGTTGCCTC TACCGCCCGGAAAACGTCGGACCCAGTCCCTCAGTGCCCTACCCAAGGAACGGGACTCATCTTCTGAGAA GGATGGACGCAGCCCCAACAAGCGGGAGAAGGACCACATCCGGCGGCCCATGAATGCCTTCATGATCTTC AGCAAGCGGCACCGGGCCCTGGTCCACCAGCGTCATCCCAACCAGGACAACCGGACCGTCAGCAAGATCC TGGGCGAGTGGTGGTATGCCCTGGGGCCCAAGGAGAAGCAGAAGTACCACGACCTGGCCTTCCAGGTGAA GGAGGCCCACTTCAAGGCCCACCCAGATTGGAAGTGGTGCAACAAGGACCGAAAGAAGTCCAGCTCAGAG GCCAAGCCCACGAGCCTGGGGCTGGCAGGAGGGCACAAGGAGACGCGGGAGCGGAGCATGTCGGAGACGG GCACTGCTGCTGCCCCTGGGGTGTCCTCTGAGCTCCTGTCCGTTGCAGCCCAGACACTCCTGAGCTCAGA CACCAAGGCTCCGGGGAGCAGCTCCTGTGGGGCAGAACGGCTACACACAGTTGGGGGACCTGGCTCAGCC CGGCCCCGAGCTTTCTCCCACAGCGGGGTACACAGCCTGGACGGCGGAGAAGTAGACAGTCAGGCGCTAC AGGAACTGACGCAGATGGTGTCTGGCCCTGCATCGTACTCTGGCCCAAAGCCTTCTACCCAGTATGGAGC TCCAGGACCCTTTGCAGCCCCTGGTGAGGGAGGTGCCTTGGCGGCCACTGGGCGGCCCCCGCTGCTGCCC ACCCGAGCTTCTCGTTCTCAGCGTGCGGCCAGTGAGGACATGACGAGTGATGAGGAGCGCATGGTCATCT GTGAGGAGGAAGGGGATGATGATGTCATTGCTGACGATGGCTTCGGCACCACTGACATTGATCTCAAGTG CAAGGAGCGGGTGACCGACAGCGAGAGTGGGGACAGCTCTGGGGAGGACCCAGAGGGCAACAAGGGCTTT GGTCGGAAGGTGTTTTCACCTGTGATCCGTTCCTCCTTTACCCACTGCCGCCCCCCACTGGACCCTGAGC CCCCAGGGCCCCCGGATCCTCCTGTAGCCTTTGGCAAAGGCTATGGTTCCGCCCCATCCTCCTCTGCGTC CTCGCCTGCTTCCTCCTCAGCCTCGGCAGCCACCTCCTTCTCACTGGGCTCAGGAACCTTCAAGGCCCAG GAGTCTGGTCAGGGCAGCACAGCGGGCCCCCTACGGCCCCCACCCCCTGGGGCTGGGGGTCCAGCGACAC CTTCCAAGGCAACCCGGTTCCTCCCAATGGATCCTGCCACCTTCCGGCGCAAGAGACCCGAAAGTGTGGG TGGCCTGGAGCCACCAGGCCCCTCAGTCATCGCGGCCCCTCCCAGCGGAGGAGGAAACATCCTGCAGACA CTGGTGCTGCCCCCAAACAAGGAGGAGCAAGAGGGCGGCGGAGCCAGAGTGCCCTCCGCCCCCGCCCCAT CACTGGCCTATGGGGCCCCAGCAGCTCCCCTGTCCCGTCCTGCCGCCACCATGGTCACCAATGTGGTGCG GCCTGTCAGCAGCACTCCTGTGCCCATCGCCTCTAAGCCCTTCCCCACCTCTGGCCGGGCTGAGGCGTCT CCAAATGACACAGCAGGTGCCAGGACTGAAATGGGCACTGGGTCTCGGGTGCCTGGGGGCTCCCCGCTGG GTGTCAGCTTAGTGTATTCGGACAAGAAGTCGGCAGCAGCCACCTCACCAGCCCCACACTTGGTGGCTGG ACCCCTGCTGGGCACTGTGGGGAAGGCGCCTGCCACTGTCACTAACCTACTGGTGGGCACCCCGGGGTAT GGGGCCCCTGCGCCCCCTGCTGTCCAGTTCATTGCCCAGGGGGCCCCTGGTGGTGGGACCACTGCGGGCT CAGGAGCAGGTGCTGGGAGTGGCCCCAATGGGCCAGTACCCCTGGGCATCCTGCAACCAGGTGCCCTGGG CAAGGCTGGGGGAATCACCCAGGTACAGTACATCCTGCCCACGCTGCCCCAGCAGCTTCAGGTGGCACCT GCCCCAGCACCAGCCCCTGGGACCAAGGCAGCGGCTCCCAGCGGCCCTGCACCCACCACCAGCATCCGTT TCACCCTCCCACCGGGCACTTCCACCAACGGCAAAGTCCTGGCTGCCACTGCACCCACTCCTGGCATCCC CATCCTGCAGTCTGTACCCTCCGCCCCACCCCCCAAAGCCCAGTCAGTTTCTCCCGTGCAGGCCCCGCCC CCGGGTGGCTCAGCCCAGCTGCTGCCTGGGAAGGTCCTAGTGCCTCTGGCCGCCCCTAGCATGTCAGTGC GGGGTGGAGGGGCCGGCCAGCCACTGCCACTGGTGAGCCCGCCCTTCTCAGTACCTGTGCAGAATGGTGC CCAGCCCCCCAGCAAGATCATCCAGCTGACCCCGGTGCCTGTGAGCACACCCAGCGGCCTGGTGCCGCCC CTGGGCCCAGCCACACTCCCTGGACCCACCTCTCAGCCTCAGAAGGTCCTGTTGCCCTCCTCCACCAGAA TCACCTATGTGCAGTCAGCGGGCGGGCACGCGCTGCCCCTGGGTACCAGCCCTGCGTCCAGCCAGGCTGG AACAGTCACCTCGTACGGGCCCACGAGCTCTGTAGCTCTAGGCTTCACCTCGCTGGGGCCCAGCGGCCCC GCCTTCGTGCAGCCCCTGCTCTCAGCAGGCCAAGCCCCACTGCTGGCTCCCGGTCAGGTGGGCGTGTCAC CTGTGCCCAGTCCCCAGCTGCCGCCTGCCTGTGCAGCCCCCGGAGGTCCTGTCATAACAGCATTTTACTC TGGCAGCCCTGCACCCACCTCCTCAGCACCCCTGGCCCAGCCATCCCAGGCCCCCCCAAGCCTGGTCTAC ACTGTGGCCACCAGCACAACCCCACCTGCAGCCACCATTCTGCCCAAGGGCCCGCCAGCCCCTGCCACTG CCACCCCAGCCCCGACTAGCCCTTTCCCCAGCGCCACAGCAGGTTCCATGACCTACAGCTTAGTGGCCCC CAAGGCCCAGCGGCCCAGCCCGAAGGCCCCCCAGAAAGTGAAGGCAGCCATCGCCAGCATTCCCGTGGGG TCCTTTGAGGCAGGTGCCTCTGGGCGGCCTGGCCCTGCACCCCGGCAGCCTCTGGAGCCTGGCCCAGTCC GAGAGCCAACTGCCCCAGAGTCTGAGCTTGAGGGGCAGCCCACACCACCAGCCCCTCCACCCCTGCCAGA GACCTGGACTCCCACGGCCCGGAGCAGCCCCCCACTGCCCCCACCTGCTGAGGAGCGGACCAGCGCCAAG GGCCCTGAGACCATGGCCAGCAAATTCCCCAGCTCATCTTCAGACTGGCGCGTCCCTGGGCAGGGCCTGG AGAATCGTGGGGAGCCTCCCACTCCTCCCAGCCCGGCCCCAGCTCCAGCTGTAGCCCCTGGTGGCAGCAG CGAGAGCAGCAGTGGGCGGGCAGCCGGGGACACCCCGGAGCGCAAGGAGGCGGCTGGTACTGGCAAGAAG GTGAAGGTGCGGCCCCCGCCCCTGAAGAAGACCTTTGACTCTGTGGACAACAGGGTCCTGTCAGAAGTGG ACTTCGAAGAGCGCTTTGCTGAGTTGCCTGAGTTTCGGCCTGAGGAGGTGCTGCCCTCCCCCACCCTGCA GTCTCTGGCCACCTCACCCCGGGCCATCCTGGGCTCTTACCGCAAGAAGAGGAAGAACTCCACGGACCTG GATTCAGCACCCGAGGACCCCACCTCGCCCAAGCGCAAGATGAGAAGACGCTCCAGCTGCAGCTCGGAGC CCAACACCCCCAAGAGTGCCAAGTGCGAGGGGGACATCTTCACCTTTGACCGTACAGGTACAGAAGCCGA GGACGTGCTTGGGGAGCTAGAGTATGACAAGGTGCCATACTCCTCCCTGCGGCGCACCCTGGACCAGCGC CGGGCCCTGGTCATGCAGCTCTTTCAGGACCATGGCTTCTTCCCGTCAGCCCAGGCCACAGCCGCCTTCC AGGCCCGCTATGCAGACATCTTTCCCTCCAAGGTTTGTCTGCAGTTGAAGATCCGTGAGGTGCGCCAGAA GATCATGCAGGCTGCCACTCCCACGGAGCAGCCCCCTGGAGCTGAGGCTCCTCTCCCTGTACCGCCCCCC ACTGGCACCGCTGCTGCCCCTGCCCCCACTCCCAGCCCCGCAGGGGGCCCTGACCCCACCTCACCCAGCT CGGACTCTGGCACGGCCCAGGCTGCCCCGCCACTGCCTCCACCCCCAGAGTCGGGGCCTGGACAGCCTGG CTGGGAGGGGGCTCCCCAGCCCTCCCCCCCACCCCCAGGTCCCTCCACAGCTGCCACAGGCAGG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG215209 representing NM_015125
Red=Cloning site Green=Tags(s) MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQ SKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRL DSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIF SKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSE AKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSA RPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLP TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGF GRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQ ESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQT LVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEAS PNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGY GAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPP PGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPP LGPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGP AFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVY TVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVG SFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAK GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKK VKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDL DSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQR RALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPP TGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_015125 |
| ORF Size | 4824 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_015125.2, NP_055940.2 |
| RefSeq Size | 5473 bp |
| RefSeq ORF | 4827 bp |
| Locus ID | 23152 |
| UniProt ID | Q96RK0 |
| Gene Summary | The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID:21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215209 | CIC (Myc-DDK-tagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 16,504.00 |
|
| RC215209L1 | Lenti-ORF clone of CIC (Myc-DDK-tagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 18,904.00 |
|
| RC215209L2 | Lenti-ORF clone of CIC (mGFP-tagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 18,904.00 |
|
| RC215209L3 | Lenti-ORF clone of CIC (Myc-DDK-tagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 17,960.00 |
|
| RC215209L4 | Lenti-ORF clone of CIC (mGFP-tagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 17,960.00 |
|
| SC304239 | CIC (untagged)-Human capicua homolog (Drosophila) (CIC) |
CNY 31,070.00 |
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