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SOX6 (NM_001145819) Human Tagged ORF Clone
CAT＃: RC227487
- TrueORF®
SOX6 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4
ORF Plasmid: tGFP
"NM_001145819" in other vectors (4)
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CNY 5,800.00
| Cited in 1 publication. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | HSSOX6; SOXD; TOLCAS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC227487 representing NM_001145819.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAAAGGTCATGGTGAGCTTCAAGGACATGAAAGAAGAATGTCTTCCAAGCAAGCCACCTCTCCATTT GCCTGTGCAGCTGATGGAGAGGATGCAATGACCCAGGATTTAACCTCAAGGGAAAAGGAAGAGGGCAGT GATCAACATGTGGCCTCCCATCTGCCTCTGCACCCCATAATGCACAACAAACCTCACTCTGAGGAGCTA CCAACACTTGTCAGTACCATTCAACAAGATGCTGACTGGGACAGCGTTCTGTCATCTCAGCAAAGAATG GAATCAGAGAATAATAAGTTATGTTCCCTATATTCCTTCCGAAATACCTCTACCTCACCACATAAGCCT GACGAAGGGAGTCGGGACCGTGAGATAATGACCAGTGTTACTTTTGGAACCCCAGAGCGCCGCAAAGGG AGTCTTGCCGATGTGGTGGACACACTGAAACAGAAGAAGCTTGAGGAAATGACTCGGACTGAACAAGAG GATTCCTCCTGCATGGAAAAACTACTTTCAAAAGATTGGAAGGAAAAAATGGAAAGACTAAATACCAGT GAACTTCTTGGAGAAATTAAAGGTACACCTGAGAGCCTGGCAGAAAAAGAACGGCAGCTCTCCACCATG ATTACCCAGCTGATCAGTTTACGGGAGCAGCTACTGGCAGCGCATGATGAACAGAAAAAACTGGCAGCG TCACAAATTGAGAAACAACGGCAGCAAATGGACCTTGCTCGCCAACAGCAAGAACAGATTGCGAGACAA CAGCAGCAACTTCTGCAACAGCAGCACAAAATTAATCTCCTGCAGCAACAGATCCAGGTTCAGGGTCAC ATGCCTCCGCTCATGATCCCAATTTTTCCACATGACCAGCGGACTCTGGCAGCAGCTGCTGCTGCCCAA CAGGGATTCCTCTTCCCCCCTGGAATAACATACAAACCAGGTGATAACTACCCCGTACAGTTCATTCCA TCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACAGCTCCAGAAGGGTCATGTCTCCCAC CCACAAATTAACCAAAGGCTAAAGGGCCTAAGTGACCGTTTTGGCAGGAATTTGGACACCTTTGAACAT GGTGGTGGCCACTCTTACAACCACAAACAGATTGAGCAGCTCTATGCCGCTCAGCTGGCCAGCATGCAG GTGTCACCTGGAGCAAAGATGCCATCAACTCCACAGCCACCAAACACAGCAGGGACGGTCTCACCTACT GGGATAAAAAATGAAAAGAGAGGGACCAGCCCTGTAACTCAAGTTAAGGATGAAGCAGCAGCACAGCCT CTGAATCTCTCATCCCGACCCAAGACAGCAGAGCCTGTAAAGTCCCCAACGTCTCCCACCCAGAACCTC TTCCCAGCCAGCAAAACCAGCCCTGTCAATCTGCCAAACAAAAGCAGCATCCCTAGCCCCATTGGAGGA AGCCTGGGAAGAGGATCCTCTTTAGATATCCTATCTAGTCTCAACTCCCCTGCCCTTTTTGGGGATCAG GATACAGTGATGAAAGCCATTCAGGAGGCGCGGAAGATGCGAGAGCAGATCCAGCGGGAGCAACAGCAG CAACAGCCACATGGTGTTGACGGGAAACTGTCCTCCATAAATAATATGGGGCTGAACAGCTGCAGGAAT GAAAAGGAAAGAACGCGCTTTGAGAATTTGGGGCCCCAGTTAACGGGAAAGTCAAATGAAGATGGAAAA CTGGGCCCAGGTGTCATCGACCTTACTCGGCCAGAAGATGCAGAGGGAAGTAAAGCAATGAATGGCTCT GCAGCTAAACTACAGCAGTATTATTGTTGGCCAACAGGAGGTGCCACTGTGGCTGAAGCACGAGTCTAC AGGGACGCCCGCGGCCGTGCCAGCAGCGAGCCACACATTAAGCGACCAATGAATGCATTCATGGTTTGG GCAAAGGATGAGAGGAGAAAAATCCTTCAGGCCTTCCCCGACATGCATAACTCCAACATTAGCAAAATC TTAGGATCTCGCTGGAAATCAATGTCCAACCAGGAGAAGCAACCTTATTATGAAGAGCAGGCCCGGCTA AGCAAGATCCACTTAGAGAAGTACCCAAACTATAAATACAAACCCCGACCGAAACGCACCTGCATTGTT GATGGCAAAAAGCTTCGGATTGGGGAGTATAAGCAACTGATGAGGTCTCGGAGACAGGAGATGAGGCAG TTCTTTACTGTGGGGCAACAGCCTCAGATTCCAATCACCACAGGAACAGGTGTTGTGTATCCTGGTGCT ATCACTATGGCAACTACCACACCATCGCCTCAGATGACATCTGACTGCTCTAGCACCTCGGCCAGCCCG GAGCCCAGCCTCCCGGTCATCCAGAGCACTTATGGTATGAAGACAGATGGCGGAAGCCTAGCTGGAAAT GAAATGATCAATGGAGAGGATGAAATGGAAATGTATGATGACTATGAAGATGACCCCAAATCAGACTAT AGCAGTGAAAATGAAGCCCCGGAGGCTGTCAGTGCCAAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC >Peptide sequence encoded by RC227487
Blue=ORF Red=Cloning site Green=Tag(s) MKGHGELQGHERRMSSKQATSPFACAADGEDAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEEL PTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKG SLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTM ITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGH MPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSH PQINQRLKGLSDRFGRNLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPT GIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGG SLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRN EKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVY RDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARL SKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGA ITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDY SSENEAPEAVSAN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001145819 |
| ORF Size | 2523 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001145819.1, NP_001139291.1 |
| RefSeq Size | 8919 bp |
| RefSeq ORF | 2487 bp |
| Locus ID | 55553 |
| UniProt ID | P35712 |
| Protein Families | Transcription Factors |
| MW | 93.4 kDa |
| Gene Summary | This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
SOX6 suppresses the development of lung adenocarcinoma by regulating expression of p53, p21CIPI , cyclin D1 and β-catenin
,Lv, L;Zhou, M;Zhang, J;Liu, F;Qi, L;Zhang, S;Bi, Y;Yu, Y;,
FEBS Open Bio
,PubMed ID 31729835
[SOX6]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227487L3 | Lenti-ORF clone of SOX6 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4 |
CNY 7,700.00 |
|
| RC227487L4 | Lenti-ORF clone of SOX6 (mGFP-tagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4 |
CNY 7,700.00 |
|
| RG227487 | SOX6 (tGFP-tagged) - Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4 |
CNY 6,370.00 |
|
| SC326501 | SOX6 (untagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 4, mRNA |
CNY 7,220.00 |
