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TTBK1 (NM_032538) Human Tagged ORF Clone
CAT＃: RC214874
- TrueORF®
TTBK1 (Myc-DDK-tagged)-Human tau tubulin kinase 1 (TTBK1)
ORF Plasmid: tGFP
"NM_032538" in other vectors (6)
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CNY 9,200.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | BDTK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC214874 representing NM_032538
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCAGTGCCTAGCGGCCGCCCTTAAGGACGAAACCAACATGAGTGGGGGAGGGGAGCAGGCCGACATCC TGCCGGCCAACTACGTGGTCAAGGATCGCTGGAAGGTGCTGAAAAAGATCGGGGGCGGGGGCTTTGGTGA GATCTACGAGGCCATGGACCTGCTGACCAGGGAGAATGTGGCCCTCAAGGTGGAGTCAGCCCAGCAGCCC AAGCAGGTCCTCAAGATGGAGGTGGCCGTGCTCAAGAAGTTGCAAGGGAAGGACCATGTGTGCAGGTTCA TTGGCTGTGGCAGGAACGAGAAGTTTAACTATGTAGTGATGCAGCTCCAGGGCCGGAACCTGGCCGACCT GCGCCGTAGCCAGCCGCGAGGCACCTTCACGCTGAGCACCACATTGCGGCTGGGCAAGCAGATCTTGGAG TCCATCGAGGCCATCCACTCTGTGGGCTTCCTGCACCGTGACATCAAGCCTTCAAACTTTGCCATGGGCA GGCTGCCCTCCACCTACAGGAAGTGCTATATGCTGGACTTCGGGCTGGCCCGGCAGTACACCAACACCAC GGGGGATGTGCGGCCCCCTCGGAATGTGGCCGGGTTTCGAGGAACGGTTCGCTATGCCTCAGTCAATGCC CACAAGAACCGGGAGATGGGCCGCCACGACGACCTGTGGTCCCTCTTCTACATGCTGGTGGAGTTTGCAG TGGGCCAGCTGCCCTGGAGGAAGATCAAGGACAAGGAACAGGTAGGGATGATCAAGGAGAAGTATGAGCA CCGGATGCTGCTGAAGCACATGCCGTCAGAGTTCCACCTCTTCCTGGACCACATTGCCAGCCTCGACTAC TTCACCAAGCCCGACTACCAGTTGATCATGTCAGTGTTTGAGAACAGCATGAAGGAGAGGGGCATTGCCG AGAATGAGGCCTTTGACTGGGAGAAGGCAGGCACCGATGCCCTCCTGTCCACGAGCACCTCTACCCCGCC CCAGCAGAACACCCGGCAGACGGCAGCCATGTTTGGGGTGGTCAATGTGACGCCAGTGCCTGGGGACCTG CTCCGGGAGAACACCGAGGATGTGCTACAGGGAGAGCACCTGAGTGACCAGGAGAATGCACCCCCAATTC TGCCCGGGAGGCCCTCTGAGGGGCTGGGCCCCAGTCCCCACCTTGTCCCCCACCCCGGGGGTCCTGAGGC TGAAGTCTGGGAGGAGACAGATGTCAACCGGAACAAACTCCGGATCAACATCGGCAAAAGCCCCTGTGTG GAGGAGGAACAGAGCCGAGGCATGGGGGTCCCCAGCTCCCCAGTGCGTGCCCCCCCAGACTCCCCCACAA CCCCAGTCCGTTCTCTGCGCTACCGGAGGGTGAACAGCCCTGAGTCAGAAAGGCTGTCCACGGCGGACGG GCGAGTGGAGCTACCTGAGAGGAGGTCACGGATGGATCTGCCTGGCTCGCCCTCGCGCCAGGCCTGCTCC TCTCAGCCAGCCCAGATGCTGTCAGTGGACACAGGCCACGCTGACCGACAGGCCAGTGGCCGCATGGACG TGTCAGCCTCTGTGGAGCAGGAGGCCCTGAGCAACGCCTTCCGCTCGGTGCCGCTGGCTGAGGAGGAGGA TTTCGACAGCAAAGAGTGGGTCATCATCGACAAGGAGACGGAGCTCAAGGACTTCCCTCCAGGGGCTGAG CCCAGCACATCGGGCACCACGGATGAGGAGCCCGAGGAGCTGCGGCCACTGCCCGAGGAGGGCGAAGAGC GGCGGCGGCTGGGGGCAGAGCCCACCGTCCGGCCCCGGGGACGCAGCATGCAGGCGCTGGCGGAGGAGGA CCTGCAGCATTTGCCGCCCCAGCCCCTGCCACCCCAGCTGAGCCAGGGCGATGGCCGTTCCGAGACGTCA CAGCCCCCCACGCCTGGCAGCCCTTCCCACTCACCCCTGCACTCGGGACCCCGCCCTCGACGGAGAGAGT CGGACCCCACAGGCCCACAGAGACAGGTGTTCTCCGTGGCGCCCCCATTTGAGGTGAATGGCCTCCCACG AGCTGTGCCTCTGAGTCTGCCCTACCAGGACTTCAAAAGAGACCTCTCCGATTACCGAGAACGGGCGCGG TTGCTCAACAGGGTCCGGAGGGTGGGCTTCTCGCACATGCTGCTCACCACCCCCCAGGTCCCACTGGCTC CTGTTCAGCCTCAGGCTAATGGGAAGGAGGAAGAGGAGGAGGAGGAGGAAGATGAGGAAGAGGAAGAAGA GGATGAGGAAGAAGAAGAGGAGGAAGAGGAAGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAG GAGGCTGCAGCGGCAGTTGCCTTGGGGGAGGTGCTGGGGCCTCGTAGTGGCTCCAGCAGTGAGGGGAGTG AGAGGAGCACTGACCGGAGCCAGGAGGGTGCCCCGTCCACGCTGCTGGCAGACGATCAGAAGGAGTCCAG GGGCCGGGCCTCCATGGCCGATGGGGACCTGGAGCCTGAGGAGGGCTCCAAAACGCTGGTGCTTGTCTCT CCTGGCGACATGAAGAAGTCGCCCGTCACTGCCGAACTGGCCCCCGACCCCGACCTGGGCACCCTGGCTG CCCTCACTCCTCAGCATGAGCGGCCCCAGCCCACGGGCAGCCAGCTGGACGTATCTGAGCCAGGCACCCT GTCCTCTGTCCTCAAGTCTGAGCCCAAGCCCCCGGGGCCTGGGGCAGGGCTGGGGGCCGGGACAGTGACC ACAGGGGTCGGGGGCGTGGCAGTCACCTCCTCACCCTTCACCAAAGTTGAGAGGACCTTTGTGCACATTG CGGAGAAAACCCACCTCAACGTCATGTCTTCCGGTGGACAAGCCTTGCGGTCTGAGGAGTTCAGCGCTGG GGGCGAGCTGGGTCTGGAGCTGGCCTCTGATGGGGGCGCTGTGGAGGAGGGGGCCCGAGCGCCCCTGGAG AACGGCCTCGCCCTGTCAGGGCTGAATGGGGCTGAGATAGAGGGCTCTGCCCTGTCTGGGGCCCCCCGGG AAACCCCCTCAGAGATGGCCACAAACTCACTGCCCAATGGCCCGGCCCTTGCAGACGGGCCAGCCCCGGT GTCCCCGCTGGAGCCAAGCCCTGAGAAAGTGGCCACCATCTCCCCCAGACGCCATGCTATGCCAGGCTCT CGCCCCAGGAGCCGTATCCCTGTCCTGCTCTCTGAGGAGGACACGGGCTCGGAGCCCTCAGGCTCACTGT CGGCCAAAGAGCGGTGGAGCAAGCGGGCTCGGCCGCAGCAGGACCTGGCGCGGCTGGTGATGGAGAAGAG GCAGGGCCGCCTGCTGTTGCGGCTGGCCTCAGGGGCCTCGTCCTCCTCCAGTGAGGAGCAGCGCCGTGCC TCTGAGACCCTCTCAGGCACGGGCTCTGAGGAGGACACGCCCGCCTCTGAGCCGGCAGCGGCCTTGCCCA GGAAGAGCGGGAGGGCAGCCGCCACCAGGAGCCGGATTCCCCGCCCCATTGGCCTCCGCATGCCCATGCC TGTTGCAGCCCAGCAGCCCGCCAGCAGATCCCATGGCGCGGCCCCAGCATTGGACACAGCCATCACCAGC AGGCTCCAGCTGCAGACGCCCCCAGGGTCGGCCACTGCTGCTGACCTCCGCCCCAAACAACCTCCTGGCC GCGGCCTGGGCCCAGGGCGAGCCCAAGCCGGAGCCAGGCCCCCAGCGCCGCGCAGCCCGCGCCTCCCCGC GTCCACATCCGCCGCGCGCAATGCCAGCGCGTCCCCCCGGAGCCAGTCCCTGTCCCGCAGAGAGAGCCCC TCCCCCTCGCACCAGGCCCGGCCCGGGGTCCCCCCGCCCCGGGGCGTCCCGCCGGCCCGGGCCCAGCCTG ATGGCACCCCCTCCCCCGGGGGCTCCAAGAAAGGACCCAGAGGGAAACTCCAGGCTCAGCGCGCAACAAC CAAAGGCCGGGCAGGAGGCGCGGAGGGCCGGGCTGGGGCCAGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC214874 representing NM_032538
Red=Cloning site Green=Tags(s) MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQP KQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILE SIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNA HKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDY FTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDL LRENTEDVLQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACS SQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAE PSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETS QPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERAR LLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE EAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVT TGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLE NGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGS RPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRA SETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITS RLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGAR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_032538 |
| ORF Size | 3963 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032538.3 |
| RefSeq Size | 7128 bp |
| RefSeq ORF | 3966 bp |
| Locus ID | 84630 |
| UniProt ID | Q5TCY1 |
| Protein Families | Druggable Genome, Protein Kinase |
| MW | 143.2 kDa |
| Gene Summary | Summary:This gene belongs to the casein kinase 1 superfamily. The encoded protein is a neuron-specific, serine/threonine and tyrosine kinase, which regulates phosphorylation of tau, a protein that associates with microtubule assemblies and stabilizes them. Genetic variants in this gene are associated with Alzheimer's disease. [provided by RefSeq, Jul 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Tau‐Tubulin Kinase 1 Expression, Phosphorylation and Co‐Localization with Phospho‐ S er422 Tau in the A lzheimer's Disease Brain
,null,
Brain Pathology
,PubMed ID 23088643
[TTBK1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214874L1 | Lenti-ORF clone of TTBK1 (Myc-DDK-tagged)-Human tau tubulin kinase 1 (TTBK1) |
CNY 11,600.00 |
|
| RC214874L2 | Lenti-ORF clone of TTBK1 (mGFP-tagged)-Human tau tubulin kinase 1 (TTBK1) |
CNY 15,110.00 |
|
| RC214874L3 | Lenti-ORF clone of TTBK1 (Myc-DDK-tagged)-Human tau tubulin kinase 1 (TTBK1) |
CNY 15,110.00 |
|
| RC214874L4 | Lenti-ORF clone of TTBK1 (mGFP-tagged)-Human tau tubulin kinase 1 (TTBK1) |
CNY 15,110.00 |
|
| RG214874 | TTBK1 (tGFP-tagged) - Human tau tubulin kinase 1 (TTBK1) |
CNY 10,800.00 |
|
| SC305468 | TTBK1 (untagged)-Human tau tubulin kinase 1 (TTBK1) |
CNY 9,208.00 |
