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CD64 (FCGR1A) (NM_000566) Human Tagged ORF Clone
CAT＃: RC207487
FCGR1A (Myc-DDK-tagged)-Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A)
ORF Plasmid: tGFP
"NM_000566" in other vectors (6)
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CNY 3,990.00
| Cited in 4 publications. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CD64; CD64A; FCRI; IGFR1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC207487 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTGGTTCTTGACAACTCTGCTCCTTTGGGTTCCAGTTGATGGGCAAGTGGACACCACAAAGGCAGTGA TCACTTTGCAGCCTCCATGGGTCAGCGTGTTCCAAGAGGAAACCGTAACCTTGCATTGTGAGGTGCTCCA TCTGCCTGGGAGCAGCTCTACACAGTGGTTTCTCAATGGCACAGCCACTCAGACCTCGACCCCCAGCTAC AGAATCACCTCTGCCAGTGTCAATGACAGTGGTGAATACAGGTGCCAGAGAGGTCTCTCAGGGCGAAGTG ACCCCATACAGCTGGAAATCCACAGAGGCTGGCTACTACTGCAGGTCTCCAGCAGAGTCTTCACGGAAGG AGAACCTCTGGCCTTGAGGTGTCATGCGTGGAAGGATAAGCTGGTGTACAATGTGCTTTACTATCGAAAT GGCAAAGCCTTTAAGTTTTTCCACTGGAATTCTAACCTCACCATTCTGAAAACCAACATAAGTCACAATG GCACCTACCATTGCTCAGGCATGGGAAAGCATCGCTACACATCAGCAGGAATATCTGTCACTGTGAAAGA GCTATTTCCAGCTCCAGTGCTGAATGCATCTGTGACATCCCCACTCCTGGAGGGGAATCTGGTCACCCTG AGCTGTGAAACAAAGTTGCTCTTGCAGAGGCCTGGTTTGCAGCTTTACTTCTCCTTCTACATGGGCAGCA AGACCCTGCGAGGCAGGAACACATCCTCTGAATACCAAATACTAACTGCTAGAAGAGAAGACTCTGGGTT ATACTGGTGCGAGGCTGCCACAGAGGATGGAAATGTCCTTAAGCGCAGCCCTGAGTTGGAGCTTCAAGTG CTTGGCCTCCAGTTACCAACTCCTGTCTGGTTTCATGTCCTTTTCTATCTGGCAGTGGGAATAATGTTTT TAGTGAACACTGTTCTCTGGGTGACAATACGTAAAGAACTGAAAAGAAAGAAAAAGTGGGATTTAGAAAT CTCTTTGGATTCTGGTCATGAGAAGAAGGTAATTTCCAGCCTTCAAGAAGACAGACATTTAGAAGAAGAG CTGAAATGTCAGGAACAAAAAGAAGAACAGCTGCAGGAAGGGGTGCACCGGAAGGAGCCCCAGGGGGCCA CG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC207487 protein sequence
Red=Cloning site Green=Tags(s) MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTATQTSTPSY RITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRN GKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTL SCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQV LGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEE LKCQEQKEEQLQEGVHRKEPQGAT TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_000566 |
| ORF Size | 1122 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000566.2, NP_000557.1 |
| RefSeq Size | 2268 bp |
| RefSeq ORF | 1125 bp |
| Locus ID | 2209 |
| UniProt ID | P12314 |
| Domains | ig, IGc2, IG |
| Protein Families | Transmembrane |
| Protein Pathways | Fc gamma R-mediated phagocytosis, Hematopoietic cell lineage, Systemic lupus erythematosus |
| MW | 42.6 kDa |
| Gene Summary | This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody
,Zhang, D;Whitaker, B;Derebe, MG;Chiu, ML;,
MAbs
,PubMed ID 29359992
[CD64]
|
|
Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation
,Yong, SB;Kim, HJ;Kim, JK;Chung, JY;Kim, YH;,
Sci Rep
,PubMed ID 28169353
[CD64]
|
|
Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody
,Zhang, D;Goldberg, MV;Chiu, ML;,
J. Biol. Chem.
,PubMed ID 27856634
[CD64]
|
|
Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation
,Chan, AS;Jonas, AB;Qiu, X;Ottoson, NR;Walsh, RM;Gorden, KB;Harrison, B;Maimonis, PJ;Leonardo, SM;Ertelt, KE;Danielson, ME;Michel, KS;Nelson, M;Graff, JR;Patchen, ML;Bose, N;,
PLoS ONE
,PubMed ID 27812183
[CD64]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207487L1 | Lenti ORF clone of Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207487L2 | Lenti ORF clone of Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A), mGFP tagged |
CNY 5,890.00 |
|
| RC207487L3 | Lenti ORF clone of Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207487L4 | Lenti ORF clone of Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A), mGFP tagged |
CNY 5,890.00 |
|
| RG207487 | FCGR1A (tGFP-tagged) - Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A) |
CNY 4,370.00 |
|
| SC119841 | FCGR1A (untagged)-Human Fc fragment of IgG, high affinity Ia, receptor (CD64) (FCGR1A) |
CNY 5,488.00 |
