Dcstamp (NM_001289506) Mouse Tagged ORF Clone

Specifications

Product Data
Type	Mouse Tagged ORF Clone
Tag	Myc-DDK
Synonyms	4833414I07Rik; DC-STAMP; FIND; mDC-STAMP; Tm7sf4
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >MR230069 representing NM_001289506 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGGCTCTGGACCTTGGGCACCAGTATTTTCCTGAGGCTTTGGGGGACTTATGTGTTTCCACGAAGCC CTAGCTGGCTGGACTTCATCCAGCATTTGGGAGTCTGTTGCTTTGTGGCCTTCCTTTCGGTGAGCCTCTT CTCTGCAGCCTTTTACTGGATCCTGCCACCCGTTGCCCTGCTCTCTTCTGTCTGGATGATCACCTGTGTT TTCCTATGCTGTTCCAAGCGCGCACGATGCTTCATTCTTCTGGCCGTTCTGTCGTGTGGCCTCCGTGAAG GTAGGAACGCTTTGATTGCGGCTGGCACTGGGGTAGTGATCTTTGGACATGTGGAAAATATTTTTTATAA CTTCAGAGGTCTCCTAGACAGCATGACTTGCAACCTAAGGGCAAAGAGCTTTTCAGTACATTTCCCACTT TTAAAACGGTATACTGAAGCCATCCAGTGGATTTACGGCCTTGCCACTCCGCTGAATCTATTTGATGACC TTGTTTCTTGGAACCAGACTCTGGTGGTCTCTCTTTTTAGTCCCAGCCATGCCCTGGAGGCTCATATGAA TGACACTAGAGGAGAAGTCCTGGGAGTCCTGCACCATATGGTGGTCACGACAGAGCTGTTGACTTCCGTG GGCCAGAAGTTGCTTGCCCTTGCCGGGCTTCTGCTCATCCTAGTCAGCACTGGCCTCTTCCTGAAGCGAT TCCTGGGCCCTTGTGGCTGGAAGTATGAGAATGTCTACATCACCAAACAATTTGTTCGGTTTGATGAAAA GGAGAGGCACCAACAGCGGCCCTGTGTCCTCCCGCTGAATAAGAAGGAAAGGAAGAAATATGTCATCGTC CCATCTTTGCAGCTGACTCCTAAGGAGAAGAAAACCCTTGGGCTGTTCTTCCTTCCTGTCCTGACCTATC TCTACATGTGGGTGCTGTTTGCCGCTGTGGACTATCTGCTGTATCGGCTCATCTCCTCCATGAACAAACA GTTCCAAAGCTTGCCAGGGCTGGAAGTTCACTTGAAACTACGTGGAGAGCAAGGAACCCAAGGAGTCGTC CATGATTCTGCCTTTAATATATCTATGTTTGAACCGAGCTGCATTCCTAAACCACGTCTCAGTGTGTCTG AGACTTGGGTTCCTCTCAGTATTATTCTGTTAACACTAATAATACTAGGATTGTTGTCTTCTATGCTGAT GCAGCTTAAAATTCTCGTGTCAGTCTCCTTCTACCCCAAAGTGGAGAGGGAGAGAATTGAATACCTGCAT GCGAAGCTCCTTGAGAAACGATCAAAGCAGCCATTGAGAGAGGCTGACGGGAAACCGAGCCTGTACTTTA AAAAGATTCATTTCTGGTTTCCAGTCCTGAAAATGATTAGGAAGAAGCAGACAATCCCTGCAAATGAAGA TGATCTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >MR230069 representing NM_001289506 Red=Cloning site Green=Tags(s) MRLWTLGTSIFLRLWGTYVFPRSPSWLDFIQHLGVCCFVAFLSVSLFSAAFYWILPPVALLSSVWMITCV FLCCSKRARCFILLAVLSCGLREGRNALIAAGTGVVIFGHVENIFYNFRGLLDSMTCNLRAKSFSVHFPL LKRYTEAIQWIYGLATPLNLFDDLVSWNQTLVVSLFSPSHALEAHMNDTRGEVLGVLHHMVVTTELLTSV GQKLLALAGLLLILVSTGLFLKRFLGPCGWKYENVYITKQFVRFDEKERHQQRPCVLPLNKKERKKYVIV PSLQLTPKEKKTLGLFFLPVLTYLYMWVLFAAVDYLLYRLISSMNKQFQSLPGLEVHLKLRGEQGTQGVV HDSAFNISMFEPSCIPKPRLSVSETWVPLSIILLTLIILGLLSSMLMQLKILVSVSFYPKVERERIEYLH AKLLEKRSKQPLREADGKPSLYFKKIHFWFPVLKMIRKKQTIPANEDDL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_001289506
ORF Size	1407 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001289506.1, NP_001276435.1
RefSeq Size	1996 bp
RefSeq ORF	1410 bp
Locus ID	75766
MW	54.2 kDa
Gene Summary	Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.[UniProtKB/Swiss-Prot Function]

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