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Bcl11b (NM_001079883) Mouse Tagged ORF Clone
CAT＃: MR226525
- TrueORF®
Bcl11b (Myc-DDK-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 1
ORF Plasmid: tGFP
"NM_001079883" in other vectors (3)
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CNY 8,840.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 9130430L19Rik; AI604821; B630002E05Rik; BCL-11B; Ctip2; Rit1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR226525 representing NM_001079883
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCGCCGCAAACAGGGCAACCCGCAGCACTTGTCCCAGAGGGAACTCATCACGCCAGAGGCTGACC ATGTGGAGGCTACCATCCTCGAGGAAGACGAGGGTCTGGAGATAGAGGAGCCTAGCAGCCTGGGGCTGAT GGTGGGAGGCCCCGACCCTGATCTACTCACCTGTGGCCAGTGTCAGATGAACTTCCCGCTGGGGGACATC CTGGTTTTTATAGAGCACAAGAAGAAACAGTGTGGAGGCCTGGGCCCCTGCTACGACAAGGTCCTGGACA AGAGCAGTCCACCTCCCTCCTCTCGCTCTGAGCTCAGGAGAGTATCTGAGCCAGTGGAGATCGGGATCCA GGTCACCCCTGATGAAGATGACCACCTACTGTCACCCACGAAAGGCATCTGTCCCAAGCAGGAGAACATT GCAGGGCCGTGCAGGCCTGCCCAGCTGCCATCGATGGCCCCCATAGCTGCCTCCTCTTCCCACCCTCCCA CCTCCGTGATTACTTCACCTCTGCGTGCCCTGGGCGTTCTCCCACCCTGTTTCCCGCTGCCTTGCTGTGG TGCACGCCCCATCTCGGGCGACGGGACTCAGGGTGAGGGTCAGATGGAGGCTCCCTTTGGATGCCAGTGT GAGTTGTCAGGTAAAGATGAGCCTTCCAGCTACATTTGCACAACATGCAAGCAGCCCTTCAACAGCGCCT GGTTCCTGCTGCAGCACGCACAGAACACACATGGCTTCCGAATCTACCTGGAGCCTGGGCCGGCCAGCAC CTCGCTCACGCCCAGGCTCACCATCCCGCCACCGCTCGGGCCGGAGACCGTGGCGCAGTCCCCACTCATG AATTTCCTGGGGGACAGCAATCCTTTCAACCTGCTGCGCATGACGGGCCCCATCCTGCGGGACCACCCTG GCTTCGGTGAGGGCCGCTTGCCAGGTACGCCACCGCTCTTCAGCCCACCGCCACGCCATCACTTGGACCC ACACCGCCTCAGTGCAGAGGAGATGGGGCTCGTGGCCCAGCACCCCAGTGCCTTCGACCGAGTCATGCGC CTGAACCCCATGGCCATAGACTCTCCTGCCATGGACTTCTCCCGGCGGCTGCGAGAACTGGCCGGCAACA GCTCCACGCCGCCGCCCGTGTCCCCAGGCCGTGGCAACCCTATGCACCGGCTGCTGAACCCTTTCCAGCC CAGTCCCAAGTCCCCGTTCCTCAGCACGCCACCGCTGCCACCCATGCCTGCGGGCACACCGCCACCGCAG CCGCCTGCCAAGAGCAAGTCCTGTGAGTTCTGCGGCAAGACCTTCAAGTTCCAGAGCAATCTCATCGTGC ACCGGCGCAGCCACACGGGCGAGAAGCCCTACAAGTGCCAGCTGTGCGACCATGCGTGCTCGCAGGCGAG CAAGCTCAAGCGCCACATGAAGACGCACATGCACAAGGCGGGCTCTCTGGCTGGCCGCTCAGACGACGGG CTCTCAGCTGCCAGCTCCCCTGAGCCGGGCACCAGCGAGCTGCCAGGTGACCTGAAAGCGGCCGATGGCG ACTTCCGCCACCATGAGAGCGACCCATCTCTGGGCCCCGAGCCTGAGGACGACGAGGACGAGGAGGAGGA AGAAGAGGAGCTGCTGCTGGAGAACGAGAGCCGGCCTGAGTCGAGCTTCAGCATGGACTCGGAGCTGGGC CGTGGCCGCGAGAACGGAGGTGGCGTGCCACCGGGGGTGGCGGGCGCAGGGGCTGCAGCTGCGGCTCTGG CGGATGAGAAGGCTCTGGCCCTGGGCAAGGTGATGGAGGACGCAGGGCTGGGCGCACTGCCGCAGTATGG GGAGAAGCGGGGCGCCTTCCTGAAGCGTGCAGGCGACACGGGTGATGCCGGAGCTGTTGGCTGTGGGGAC GCGGGTGCACCGGGTGCAGTGAACGGGCGCGGCGGGGCCTTCGCGCCAGGCGCAGAGCCCTTTCCAGCTC TCTTCCCACGCAAGCCAGCACCGCTGCCCAGCCCTGGGCTCGGTGGTCCCGCGCTGCACGCGGCCAAGCG CATCAAGGTGGAGAAAGACCTGGAGCTGCCACCTGCCGCCCTCATCCCATCTGAGAACGTGTACTCGCAG TGGCTCGTGGGCTACGCAGCATCGCGCCACTTCATGAAGGACCCATTCCTGGGCTTCACGGATGCGCGCC AGTCGCCTTTCGCCACATCGTCGGAACATTCCTCTGAGAACGGCAGCCTGCGCTTCTCAACGCCACCCGG GGACCTGCTGGACGGCGGGCTGTCCGGGCGCAGTGGCACGGCGAGCGGGGGCAGCACACCTCACCTGGGT GGTCCGGGTCCTGGGAGGCCGAGCTCCAAGGAGGGCCGCCGCAGCGACACATGTGAGTACTGCGGCAAGG TCTTCAAGAACTGTAGCAACCTGACGGTGCACCGGAGGAGCCACACCGGCGAGCGGCCTTACAAGTGCGA GCTGTGCAACTACGCGTGCGCGCAGAGCAGCAAGCTCACGCGCCACATGAAGACGCACGGGCAGATCGGC AAGGAGGTGTACCGCTGCGACATCTGCCAGATGCCCTTCAGCGTCTACAGCACCCTGGAGAAACACATGA AAAAGTGGCACGGTGAACACTTGCTGACTAATGATGTCAAAATCGAGCAGGCTGAGAGGAGC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >MR226525 representing NM_001079883
Red=Cloning site Green=Tags(s) MSRRKQGNPQHLSQRELITPEADHVEATILEEDEGLEIEEPSSLGLMVGGPDPDLLTCGQCQMNFPLGDI LVFIEHKKKQCGGLGPCYDKVLDKSSPPPSSRSELRRVSEPVEIGIQVTPDEDDHLLSPTKGICPKQENI AGPCRPAQLPSMAPIAASSSHPPTSVITSPLRALGVLPPCFPLPCCGARPISGDGTQGEGQMEAPFGCQC ELSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASTSLTPRLTIPPPLGPETVAQSPLM NFLGDSNPFNLLRMTGPILRDHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMR LNPMAIDSPAMDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPAGTPPPQ PPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDG LSAASSPEPGTSELPGDLKAADGDFRHHESDPSLGPEPEDDEDEEEEEEELLLENESRPESSFSMDSELG RGRENGGGVPPGVAGAGAAAAALADEKALALGKVMEDAGLGALPQYGEKRGAFLKRAGDTGDAGAVGCGD AGAPGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQ WLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLG GPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIG KEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001079883 |
| ORF Size | 2652 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001079883.1, NP_001073352.1 |
| RefSeq Size | 7923 bp |
| RefSeq ORF | 2655 bp |
| Locus ID | 58208 |
| UniProt ID | Q99PV8 |
| MW | 95 kDa |
| Gene Summary | Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals (PubMed:12717433). Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (By similarity). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed:16809611). Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226525 | Bcl11b (tGFP-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b) transcript variant 1, (10ug) |
CNY 9,690.00 |
|
| MR226525L3 | Lenti ORF clone of Bcl11b (Myc-DDK-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 1 |
CNY 10,740.00 |
|
| MR226525L4 | Lenti ORF clone of Bcl11b (mGFP-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 1 |
CNY 10,740.00 |
