Tox (NM_145711) Mouse Tagged ORF Clone

CAT＃: MR208435

  • TrueORF®

Tox (Myc-DDK-tagged) - Mouse thymocyte selection-associated high mobility group box (Tox)

Datasheet
SDS
Plasmid Map

  "NM_145711" in other vectors (5)

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Mouse Protein / Lysate Request

CNY 3,928.00

CNY 4,560.00

货期*
现货
规格
    • 10 ug
Cited in 3 publications.

Product images

经常一起买 (4)
PS100001
pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug
    • 10 ug

CNY 5,420.00

添加到购物车
CC100003
DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

暂停销售
PRIMER
Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

添加到购物车
TA592569S
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
    • 30 ul

CNY 300.00

添加到购物车

参与“2024逐梦开学季·科研添动力”活动,可提供10 µL试用规格

Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Synonyms 1700007F02Rik
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MR208435 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGACGTAAGATTTTATCCTCCTCCAGCCCAGCCCGCTGCTGCGCCCGCCGCTCCTTGTCTGGGACCTT
CTCCCTGCCTGGACCCCTACTATTGCAACAAGTTTGACGGGGAGAACATGTATATGAGCATGACAGAGCC
GAGCCAGGACTATGTGCCAGCCAGCCAGTCCTACCCTGGACCAAGTCTGGAAAGTGAAGATTTTAACATC
CCACCCATCACGCCTCCCTCCCTCCCTGACCACTCTCTGGTGCACCTGAATGAGGTAGAATCCGGTTACC
ACTCTCTGTGTCACCCCATGAATCACAATGGCCTGCTCCCGTTCCATCCACAAACCATGGACCTGCCAGA
GATCACGGTGTCCAACATGCTGGGCCAAGATGGCGCACTGCTCTCCAATTCCATCTCTGTGATGCAAGAT
ATTGGGAATGCAGAAGGAGCTCAGTACAGCTCCCATCCTCAGATGGCAGCCATGAGGCCGAGAGGCCAGC
CTACAGACATCAGACAGCAGGCAAGCATGATGCAGCCCGGCCAGCTGACCACCATCAACCAGTCGCAGCT
GAGCGCACAGTTGGGCTTGAACATGGGAGGAACCAATGTGGCCCACAACTCCCCTTCTCCACCCGGAAGC
AAGTCTGCAACCCCTTCCCCATCCAGCTCAGTGCATGAGGATGAGTGTGAGGATGCCTCCAAGATCAATG
GAGGAGAGAAGCGGCCTGCCTCTGATATGGGGAAAAAACCCAAAACTCCCAAGAAGAAGAAGAAGAAGGA
TCCTAATGAGCCCCAGAAGCCTGTGTCTGCCTATGCTTTGTTCTTTCGTGATACCCAGGCTGCCATTAAG
GGCCAGAATCCAAATGCTACTTTTGGTGAAGTATCGAAGATTGTGGCATCAATGTGGGATGGCCTAGGAG
AAGAACAGAAACAGGTCTATAAGAAGAAAACCGAGGCTGCAAAGAAGGAATACCTGAAGCAGCTAGCAGC
ATACAGAGCCAGCCTTGTATCCAAGAGCTACACTGATCCTGTTGATGTTAAGACATCTCAGCCACCCCAG
CTGGTCAACTCAAAGCCGTCAGTATTCCATGGGCCCAGCCAGGCCCACTCAGCTCTGTACCTAAGTTCTC
ACTATCACCAACAACCAGGAATGACTCCTCAGCTCACCGCCATGCATCCGAGCCTCCCCAGAAACATAGC
ACCTAAGCCCAATAACCAAATGCCAGTGACTGTCTCCATAGCCAACATGGCTGTGTCCCCACCACCGCCC
CTTCAGATCAGCCCACCTCTTCATCAGCATCTCAGCATGCAGCAGCATCAGTCGCTTGCCATGCAGCAGC
CCCTTGGGAGTCAGCTCCCCATGCAGGTCCAGACTGCCTTACACTCGCCCACCATGCAGCAAGGATTTAC
TCTTCAACCCGACTATCAGACTATTATCAACCCTACATCTACAGCTGCACAAGTTGTCACCCAAGCGATG
GAGTACGTGCGTTCTGGGTGCAGAAATCCGCCCCCACAGCCCGTGGACTGGAGTACCGACTACTGCAGTA
GTGGGGGCATGCAGAGGGACAAAGCGCTGTATCTCACC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
>MR208435 protein sequence
Red=Cloning site Green=Tags(s)

MDVRFYPPPAQPAAAPAAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNI
PPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQTMDLPEITVSNMLGQDGALLSNSISVMQD
IGNAEGAQYSSHPQMAAMRPRGQPTDIRQQASMMQPGQLTTINQSQLSAQLGLNMGGTNVAHNSPSPPGS
KSATPSPSSSVHEDECEDASKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIK
GQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYTDPVDVKTSQPPQ
LVNSKPSVFHGPSQAHSALYLSSHYHQQPGMTPQLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
LQISPPLHQHLSMQQHQSLAMQQPLGSQLPMQVQTALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAM
EYVRSGCRNPPPQPVDWSTDYCSSGGMQRDKALYLT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_145711
ORF Size 1581 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_145711.1, NM_145711.2, NM_145711.3, NM_145711.4, NP_663757.3
RefSeq Size 2852 bp
RefSeq ORF 1581 bp
Locus ID 252838
UniProt ID Q66JW3
MW 57.2 kDa
Gene Summary May play a role in regulating T-cell development.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

The use of this cDNA Clones has been cited in the following citations:
MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation ,Wu, CJ;Cho, S;Huang, HY;Lu, CH;Russ, J;Cruz, LO;da Cunha, FF;Chen, MC;Lin, LL;Warner, LM;Liao, HK;Utzschneider, DT;Quon, S;Berner, J;Camara, NOS;Zehn, D;Belmonte, JCI;Chen, LC;Huang, SF;Kuo, ML;Lu, LF;, Sci Adv ,PubMed ID 31844658 [TOX]
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion ,Khan, O;Giles, JR;McDonald, S;Manne, S;Ngiow, SF;Patel, KP;Werner, MT;Huang, AC;Alexander, KA;Wu, JE;Attanasio, J;Yan, P;George, SM;Bengsch, B;Staupe, RP;Donahue, G;Xu, W;Amaravadi, RK;Xu, X;Karakousis, GC;Mitchell, TC;Schuchter, LM;Kaye, J;Berger, SL;Wherry, EJ;, Nature ,PubMed ID 31207603 [TOX]
TOX is a critical regulator of tumour-specific T cell differentiation ,null, Nature ,PubMed ID 31207604 [Tox]

Other Versions

SKU Description Size Price
MC217406 Tox (untagged) - Mouse thymocyte selection-associated high mobility group box (Tox), (10ug)
    • 10 ug

CNY 3,928.00
CNY 6,750.00

MR208435L1 Lenti ORF clone of Tox (Myc-DDK-tagged) - Mouse thymocyte selection-associated high mobility group box (Tox)
    • 10 ug

CNY 6,460.00

MR208435L2 Lenti ORF clone of Tox (mGFP-tagged) - Mouse thymocyte selection-associated high mobility group box (Tox)
    • 10 ug

CNY 6,328.00
CNY 6,460.00

MR208435L3 Lenti ORF clone of Tox (Myc-DDK-tagged) - Mouse thymocyte selection-associated high mobility group box (Tox)
    • 10 ug

CNY 6,460.00

MR208435L4 Lenti ORF clone of Tox (mGFP-tagged) - Mouse thymocyte selection-associated high mobility group box (Tox)
    • 10 ug

CNY 6,460.00

You may also need
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