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Atm (NM_007499) Mouse Tagged ORF Clone
CAT＃: MG226850
- TrueORF®
Atm (tGFP-tagged) - Mouse ataxia telangiectasia mutated homolog (human) (Atm), (10ug)
ORF Plasmid: DDK
"NM_007499" in other vectors (2)
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CNY 33,630.00
货期*
3周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | AI256621; C030026E19Rik |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG226850 representing NM_007499
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGTCTAGCACTCAATGATCTGCTCATTTGCTGCCGGCAGTTAGAGCATGACAGAGCTACAGAAAGAA GGAAAGAAGTGGATAAATTTAAGCGCCTGATTCAGGATCCTGAAACAGTTCAACATTTAGATAGGCATTC TGATTCCAAACAAGGAAAATATCTGAATTGGGATGCTGTTTTCAGGTTTTTACAGAAGTACATTCAAAAA GAAATGGAAAGTCTGAGAACAGCAAAATCAAATGTATCAGCCACCACACAGAGCTCCAGACAGAAGAAGA TGCAAGAGATCAGCAGTTTGGTCAGATACTTCATCAAATGTGCAAACAAAAGAGCACCCAGGCTAAAATG TCAAGACCTCTTGAATTATGTCATGGATACAGTGAAAGACTCATCTAATGGTCTAACGTATGGAGCTGAC TGTAGCAACATACTACTCAAAGACATTCTTTCTGTGAGAAAATACTGGTGTGAAGTATCTCAGCAACAGT GGCTAGAATTGTTTTCACTGTACTTCAGGCTGTATCTCAAGCCATCACAGGACATTAATAGAGTTTTAGT GGCTAGAATAATTCATGCTGTCACCAGAGGATGCTGTTCACAGACTGATGGATTACCTTCAAAGTTTTTA GATCTTTTTTCCAAGGCTATTCAGTATGCCAGACAAGAAAAGAGCTCTCCTGGCTTAAGTCACATCTTAG CAGCCCTTAACATTTTCCTCAAGTCTCTGGCTGTCAACTTCCGAAAACGGGTGTGTGAAGCAGGAGATGA AATTCTTCCTACCTTACTATATATTTGGACTCAACATAGACTTAATGATTCTTTAAAAGAAGTAATTATT GAACTAATTCAACTGCAGATTTATATCCATCATCCACAAGGAGCCAGAGCTCCTGAAGAAGGTGCTTATG AATCCATGAAATGGAAAAGTATCTTGTACAACTTATATGACTTGCTAGTGAATGAGATAAGTCATATAGG AAGCCGAGGGAAATATTCCTCAGGATCTCGTAATATTGCTGTCAAGGAAAATCTGATTGACCTGATGGCA GATATCTGTTACCAGCTTTTTGATGCAGATACCAGATCCGTGGAGATTTCTCAATCTTATGTGACACAAA GGGAATCCACTGATTACAGTGTACCTTGCAAAAGAAGGAAAATAGACGTAGGCTGGGAAGTGATAAAAGA TTATCTTCAGAAGTCACAGAGTGATTTTGATCTCGTGCCTTGGCTACAGATTACAACCCGATTAATATCA AAATATCCTTCCAGTTTACCTAACTGTGAGCTGTCTCCATTAATACTGATACTGTACCAGCTTCTGCCTC AACAGCGACGTGGAGAACGCATCCCATATGTGTTACGATGCCTTAAGGAAGTTGCCTTATGTCAAGGCAA GAAATCAAACCTGGAAAGCTCTCAGAAGTCAGATTTATTGAAACTATGGATCAAAATTTGGTCTATTACC TTTCGTGGTATAAGTTCTGGACAAACACAAACTGAAAACTTTGGTTTACTTGAGGCCATCATTCAAGGTA GTTTAGTTGAACTTGACAGAGAATTCTGGAAGTTATTTACTGGCTCAGCCTGTAAACCTTCTAGTCCTTC AGTATGCTGCTTGACTTTGGCACTTAGCATCTGTGTAGTTCCAGATGCAATAAAAATGGGAACAGAACAA AGTGTGTGTGAAGCAAATAGAAGTTTTTCTGTAAAGGAGTCAATAATGAGGTGGCTCTTATTCTACCAGT TAGAGGATGACTTAGAAGACAGCACAGAGCTGCCTCCAATTCTTCAGAGTAATTTTCCTCATCTTGTAGT CGAAAAAATTCTTGTAAGTCTCACTATGAAAAACTCAAAAGCTGCAATGAAGTTTTTTCAAAGTGTGCCA GAATGTGAACAACACTGCGAAGATAAAGAAGAGCCTTCATTTTCAGAAGTAGAAGAACTGTTTCTTCAGA CTACTTTTGACAAGATGGATTTTTTAACTACTGTCAAAGAGTATGCTGTAGAAAAATTTCAGTCTAGTGT TGGCTTCTCTGTCCAGCAAAATCTCAAGGAATCATTGGATCACTATCTTCTGGGATTATCAGAACAGCTT TTAAGTAATTACTCTTCTGAGATTACAAGTTCTGAAACCCTTGTCCGGTGTTCAAGTCTTTTGGTGGGTG TTCTTGGCTGCTATTGTTACATGGGTATAATAACTGAAGACGAAGCCCATAAATCAGAATTATTCCAGAA AGCCAAGTCTCTGATGCAATGTGCAGGAGAAAGTATCTCTCTGTTTAAAAATAAAACAAATGAGGAATCA AGAATTGGTTCATTGAGAAATGTGATGCATCTGTGTACAAGTTGCTTGTGTATACATACCAAGCATACGC CAAACAAGATTGCCTCTGGCTTTTTCCTACGATTATTAACATCAAAGCTTATGAATGACATTGCAGATAT TTGTAAAAGTTTAGCATCCTGTACGAAAAAGCCATTGGATCACGGAGTACATCCAGGGGAAGATGATGAA GATGGTGGTGGTTGTGACAGTCTGATGGAGGCAGAGGGTCCATCGTCCACTGGTCTTTCTACTGCTTACC CCGCTAGTTCTGTGAGCGATGCAAATGATTATGGAGAGAACCAGAATGCTGTTGGTGCCATGAGTCCTTT AGCTGCCGACTACCTGTCCAAACAAGATCATCTTCTCTTAGACATGCTCAGGTTCTTAGGCCGATCTGTA ACTGCATCTCAGAGCCATACTGTGTCGTTTAGAGGAGCTGACATTAGAAGAAAATTGTTACTGTTGCTTG ATTCTAGCATACTCGATCTCATGAAGCCCCTCCACCTGCATATGTACTTAGTGCTCCTGAAGGATCTCCC TGGAAACGAGCACTCATTGCCAATGGAAGATGTTGTTGAACTTCTGCAACCATTATCCCTTGTGTGTTCT CTGCACCGACGTGACCAAGATGTCTGTAAAACGATTCTAAGCAATGTCCTTCATATAGTGACAAACCTAG GCCAGGGCAGTGTGGACATGGAGAGCACACGGATTGCTCAAGGACACTTCCTGACAGTGATGGGAGCATT TTGGCATTTGACAAAGGAAAAGAAATGTGTATTCTCTGTAAGAATGGCATTAGTAAAGTGTCTTCAAACA TTGCTTGAGGCTGATCCATATTCCGAATGGGCAATTCTTAATGTAAAAGGACAAGACTTTCCTGTAAATG AAGCTTTTTCACAATTTCTTGCTGACGATCATCATCAAGTTCGGATGTTGGCTGCAGGGTCAGTCAACAG ATTATTTCAGGATATGAGACAAGGCGATTTCTCCAGAAGCTTGAAAGCACTCCCTCTGAAGTTTCAGCAG ACATCTTTTAACAATGCATACACGACAGCAGAGGCGGGGATCAGAGGACTGTTATGTGATTCTCAGAACC CTGATCTGCTGGATGAGATCTATAACAGAAAATCTGTACTACTGATGATGATAGCTGTGGTCTTGCACTG TAGCCCAGTCTGTGAAAAGCAGGCTTTGTTTGCTTTATGCAAGTCTGTGAAGGAAAACAGACTAGAACCT CATCTTGTGAAAAAGGTTTTAGAGAAAGTCTCCGAATCGTTTGGATGTAGAAGTTTAGAAGACTTCATGA TTTCTCACCTAGACTACCTGGTTTTGGAATGGCTGAACCTTCAAGATACTGAATATAGCTTATCTTCTTT TCCTTTTATGTTATTAAACTACACAAGCATTGAGGATTTCTATCGGTCTTGTTACAAGATTTTGATCCCA CATTTGGTAATCAGAAGCCATTTTGATGAGGTGAAGTCCATTGCTAATCAGATTCAAAAGTGCTGGAAAA GCCTGTTGGTAGATTGCTTTCCGAAGATTCTTGTGCACATCCTTCCTTACTTTGCCTACGAGGGCACGAG AGACAGCTACGTGTCACAGAAAAGAGAGACTGCTACCAAGGTCTACGATACTCTTAAAGGGGAAGACTTC CTAGGAAAACAGATTGACCAAGTATTCATTAGTAATTTGCCAGAGATTGTGGTGGAGTTGCTGATGACAT TGCATGAGACAGCTGACTCGGCTGACTCGGACGCCAGTCAAAGCGCCACCGCCTTGTGTGATTTTTCAGG GGATTTGGATCCTGCCCCCAACCCGCCATATTTCCCCTCACATGTCATTCAGGCAACGTTTGCTTACATC AGCAACTGTCATAAAACCAAGTTTAAAAGCATTCTAGAAATTCTTTCTAAAATCCCCGATTCCTATCAGA AAATACTTCTGGCCATTTGTGAACAAGCAGCTGAGACAAATAATGTCTTTAAAAAGCACAGAATTCTTAA AATATATCACCTGTTTGTTAGTTTATTACTGAAAGATATACAGAGTGGCCTGGGAGGGGCTTGGGCCTTT GTCCTTCGCGATGTTATTTATACTCTGATTCACTACATCAACAAAAGGTCTTCTCATTTCACAGATGTGT CGTTGCGTAGCTTTTCCCTTTGCTGTGACCTATTAAGTCGAGTTTGTCATACAGCTGTAACTCAATGTAA GGATGCTCTAGAAAGCCATCTTCACGTTATCGTTGGCACACTTATTCCCCTTGTGGATTATCAGGAAGTT CAAGAACAGGTATTGGACCTGTTGAAGTACTTAGTGATAGATAACAAAGACAATAAAAACCTCTCTGTCA CAATTAAGCTTTTGGATCCCTTTCCTGACCATGTTATTTTTAAGGACTTGCGTCTTACTCAACAGAAAAT CAAATATAGTGGAGGACCTTTTTCACTCTTAGAGGAAATAAACCATTTTCTCTCAGTAAGTGCTTACAAT CCACTTCCGCTGACCAGGCTTGAAGGACTGAAGGATCTTCGAAGACAACTGGAGCAACATAAAGATCAGA TGCTAGATCTTCTGAGAGCGTCTCAAGATAACCCACAAGATGGCATTGTGGTGAAGCTAGTTGTCAGCTT GTTGCAGTTATCCAAGATGGCAGTGAACCAGACTGGTGAAAGAGAAGTTTTAGAGGCTGTCGGAAGGTGT TTGGGAGAAATAGGTCCTCTGGATTTCTCCACCATAGCTGTCCAGCATAACAAAGATGTGTCCTATACCA AAGCCTACGGGTTACCTGAAGACAGAGAACTTCAGTGGACCTTGATAATGCTGACTGCCCTCAACAATAC CCTGGTAGAGGACAGTGTCAAAATTCGATCTGCTGCTGCTACCTGTTTGAAAAACATTTTGGCTACAAAG ATTGGACATATTTTCTGGGAGAATTATAAGACATCAGCGGATCCAATGCTGACCTATCTACAACCTTTTA GAACATCGAGGAAAAAGTTTTTAGAAGTGCCCCGATCTGTTAAAGAAGATGTTTTAGAAGGCCTGGATGC TGTGAATCTGTGGGTTCCTCAAAGTGAAAGTCATGACATTTGGATAAAGACACTGACGTGTGCCTTTCTG GACAGTGGAGGCATAAACAGTGAAATTCTCCAGTTATTAAAGCCAATGTGTGAAGTGAAAACCGACTTCT GTCAGATGTTGCTGCCATACTTGATCCATGATGTTTTACTGCAAGATACACATGAATCGTGGAGAACTCT GCTGTCTGCGCACGTCCGAGGATTTTTCACTAGTTGTTTTAAGCATTCCTCCCAAGCAAGCCGCTCAGCA ACTCCTGCAAATTCGGATTCAGAGTCAGAGAACTTTCTCCGATGCTGTTTGGATAAAAAGTCACAAAGAA CCATGCTTGCTGTTGTCGACTATCTGAGAAGGCAAAAGAGACCTTCCTCGGGAACAGCTTTTGATGACGC TTTCTGGCTGGATTTGAATTATCTTGAGGTTGCGAAGGTGGCTCAGTCCTGCTCTGCTCACTTCACGGCC TTGCTCTACGCAGAGATCTATTCAGATAAGAAAAGCACAGACGAGCAAGAGAAAAGAAGTCCAACATTTG AAGAAGGAAGTCAAGGAACAACTATTTCTAGTTTGAGTGAAAAAAGTAAAGAAGAAACTGGAATAAGCTT ACAGGATCTTCTCTTAGAGATCTACAGAAGTATAGGAGAGCCGGACAGCCTGTATGGCTGTGGAGGAGGG AAAATGTTACAACCCCTTACTAGAATACGGACATATGAACATGAAGCTACGTGGGAGAAAGCCTTAGTAA CTTACGACCTGGAGACCAGCATCTCCTCCTCCACCCGCCAGTCAGGAATCATCCAGGCCCTGCAGAATTT GGGGCTCTCCCATATCCTGTCTGTCTATCTGAAAGGATTAGACTATGAAAGACGAGAGTGGTGCGCTGAG CTGCAGGAGCTGCGTTACCAGGCGGCGTGGAGGAACATGCAGTGGGGCCTCTGCGCTTCTGCCGGCCAAG AAGTAGAAGGAACCAGTTACCATGAATCGTTGTATAATGCTCTGCAGTGTCTAAGAAACAGAGAATTCTC CACATTTTATGAAAGTCTCCGATATGCCAGTCTTTTCAGGGTGAAAGAAGTTGAAGAGTTGAGTAAGGGC AGCCTTGAGTCTGTATATTCGCTGTATCCCACACTTAGTAGATTGCAGGCAATTGGAGAACTGGAAAACA GTGGCGAGCTTTTCTCAAGGTCAGTCACAGACAGAGAGCGCTCTGAAGCATACTGGAAGTGGCAGAAGCA CTCCCAGCTTCTGAAAGACAGCGACTTCAGCTTTCAGGAGCCTCTCATGGCTCTGCGCACAGTCATTCTG GAGACCCTGGTACAGAAGGAAATGGAGCGCTCTCAAGGAGCATGCTCTAAGGACATTCTCACCAAACACC TCGTTGAATTCTCTGTTCTGGCTCGAACCTTCAAGAACACACAGCTCCCTGAAAGAGCAATATTCAAAAT TAAGCAATATAATTCAGCTATTTGTGGAATTTCTGAGTGGCATTTGGAAGAAGCACAAGTATTCTGGGCA AAAAAGGAGCAGAGTCTTGCTCTGAGTATTCTCAAGCAGATGATCAAGAAGTTGGACTCCAGCTTTAAAG ATAAAGAGAATGATGCAGGTCTCAAAGTCATATACGCAGAGTGTCTGAGGGTTTGTGGCAGCTGGCTGGC AGAAACTTGCTTAGAAAACCCTGCAGTCATCATGCAGACCTATCTAGAAAAGGCGGTGAAGGTTGCTGGA AGTTACGATGGCAACAGCAGAGAGCTCAGAAATGGACAGATGAAGGCCTTTCTCTCGTTGGCAAGGTTCT CTGATACTCAGTACCAGAGAATTGAAAACTACATGAAGTCATCAGAATTTGAAAACAAGCAAACTCTCTT AAAAAGAGCCAAAGAGGAAGTGGGCCTTCTAAGGGAACATAAAATTCAGACCAACAGATACACAGTAAAG GTTCAGCGAGAACTGGAGCTGGACGAATGTGCTCTCCGTGCACTGAGAGAGGATCGCAAGCGCTTCCTGT GTAAAGCAGTGGAGAACTACATCAACTGCTTACTAAGCGGGGAAGAACATGATCTGTGGGTGTTCCGGCT TTGCTCCCTCTGGCTTGAAAATTCTGGAGTTTCTGAAGTCAATGGCATGATGAAGAAAGATGGAATGAAG ATTTCATCCTATAAGTTTTTGCCTCTCATGTATCAATTGGCTGCTCGAATGGGGACCAAAATGACGGGAG GCCTAGGATTTCACGAAGTCCTCAATAATCTAATCTCTAGGATTTCACTGGATCACCCCCATCATACTTT GTTCATTATACTGGCCTTAGCAAATGCGAACAAAGATGAATTTTTGAGCAAACCAGAGACAACAAGAAGG AGTCGAATAACCAAAAGTACATCTAAAGAAAACTCTCACCTTGATGAGGATCGAACAGAGGCTGCAACCA GAATCATCCACTCCATCAGAAGTAAGCGATGTAAGATGGTGAAGGACATGGAGGCGCTCTGCGATGCCTA CATCATCTTGGCAAACATGGACGCCTCTCAGTGGAGGGCTCAGAGAAAAGGCATCAATATTCCAGCCAAC CAGCCAATCACTAAACTGAAGAATTTAGAAGATGTTGTTGTTCCCACTATGGAAATTAAGGTTGATCCCA CAGGAGAGTATGAAAATCTGGTGACTATAAAATCATTTAAAACAGAATTTCGCTTAGCTGGAGGCTTAAA TTTACCCAAAATAATAGATTGTGTGGGTTCTGATGGCAAGGAAAGGAGACAGCTTGTGAAGGGCCGTGAT GACCTGAGGCAAGATGCTGTCATGCAGCAGGTCTTCCAGATGTGCAATACACTACTGCAGAGAAACACTG AGACTAGAAAGAGGAAACTGACTATCTGCACATACAAGGTGGTTCCCCTTTCTCAGCGAAGCGGTGTTCT CGAGTGGTGCACAGGAACCGTTCCTATTGGTGAATATCTTGTTAACAGCGAAGACGGTGCACATAGAAGA TACAGGCCAAATGATTTCAGTGCCAATCAGTGCCAAAAGAAAATGATGGAAGTGCAGAAGAAGTCTTTTG AAGAGAAATATGATACCTTCATGACGATTTGCCAAAACTTTGAACCAGTTTTCCGTTACTTCTGCATGGA AAAATTCTTGGACCCAGCTGTTTGGTTTGAGAAACGATTGGCATATACACGCAGTGTGGCCACATCTTCT ATCGTCGGTTACATCCTTGGACTTGGCGACAGGCACGTACAGAATATCTTGATAAACGAGCAGTCGGCAG AGCTTGTGCACATAGACCTGGGAGTGGCTTTTGAACAGGGGAAGATCCTTCCCACTCCAGAAACAGTTCC TTTTAGACTCAGCAGAGATATTGTGGACGGGATGGGCATCACCGGTGTGGAAGGTGTCTTCAGAAGGTGC TGTGAAAAAACGATGGAAGTTATGCGGAGTTCTCAGGAAACCCTGCTGACCATTGTAGAGGTTCTTTTGT ACGATCCACTCTTTGATTGGACTATGAATCCTTTAAAAGCTCTGTATCTACAGCAGAGACCAGAAGATGA GTCCGACCTCCATTCCACCCCCAATGCAGATGATCAAGAATGCAAACAAAGTCTTAGTGATACTGACCAG AGTTTCAACAAAGTAGCTGAGCGTGTCTTGATGAGACTGCAAGAGAAACTGAAAGGCGTGGAGGAAGGCA CTGTGCTCAGTGTGGGTGGACAGGTGAACTTGCTTATCCAGCAGGCCATGGATCCCAAAAATCTCAGCCG ACTCTTCCCAGGATGGAAAGCTTGGGTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG226850 representing NM_007499
Red=Cloning site Green=Tags(s) MSLALNDLLICCRQLEHDRATERRKEVDKFKRLIQDPETVQHLDRHSDSKQGKYLNWDAVFRFLQKYIQK EMESLRTAKSNVSATTQSSRQKKMQEISSLVRYFIKCANKRAPRLKCQDLLNYVMDTVKDSSNGLTYGAD CSNILLKDILSVRKYWCEVSQQQWLELFSLYFRLYLKPSQDINRVLVARIIHAVTRGCCSQTDGLPSKFL DLFSKAIQYARQEKSSPGLSHILAALNIFLKSLAVNFRKRVCEAGDEILPTLLYIWTQHRLNDSLKEVII ELIQLQIYIHHPQGARAPEEGAYESMKWKSILYNLYDLLVNEISHIGSRGKYSSGSRNIAVKENLIDLMA DICYQLFDADTRSVEISQSYVTQRESTDYSVPCKRRKIDVGWEVIKDYLQKSQSDFDLVPWLQITTRLIS KYPSSLPNCELSPLILILYQLLPQQRRGERIPYVLRCLKEVALCQGKKSNLESSQKSDLLKLWIKIWSIT FRGISSGQTQTENFGLLEAIIQGSLVELDREFWKLFTGSACKPSSPSVCCLTLALSICVVPDAIKMGTEQ SVCEANRSFSVKESIMRWLLFYQLEDDLEDSTELPPILQSNFPHLVVEKILVSLTMKNSKAAMKFFQSVP ECEQHCEDKEEPSFSEVEELFLQTTFDKMDFLTTVKEYAVEKFQSSVGFSVQQNLKESLDHYLLGLSEQL LSNYSSEITSSETLVRCSSLLVGVLGCYCYMGIITEDEAHKSELFQKAKSLMQCAGESISLFKNKTNEES RIGSLRNVMHLCTSCLCIHTKHTPNKIASGFFLRLLTSKLMNDIADICKSLASCTKKPLDHGVHPGEDDE DGGGCDSLMEAEGPSSTGLSTAYPASSVSDANDYGENQNAVGAMSPLAADYLSKQDHLLLDMLRFLGRSV TASQSHTVSFRGADIRRKLLLLLDSSILDLMKPLHLHMYLVLLKDLPGNEHSLPMEDVVELLQPLSLVCS LHRRDQDVCKTILSNVLHIVTNLGQGSVDMESTRIAQGHFLTVMGAFWHLTKEKKCVFSVRMALVKCLQT LLEADPYSEWAILNVKGQDFPVNEAFSQFLADDHHQVRMLAAGSVNRLFQDMRQGDFSRSLKALPLKFQQ TSFNNAYTTAEAGIRGLLCDSQNPDLLDEIYNRKSVLLMMIAVVLHCSPVCEKQALFALCKSVKENRLEP HLVKKVLEKVSESFGCRSLEDFMISHLDYLVLEWLNLQDTEYSLSSFPFMLLNYTSIEDFYRSCYKILIP HLVIRSHFDEVKSIANQIQKCWKSLLVDCFPKILVHILPYFAYEGTRDSYVSQKRETATKVYDTLKGEDF LGKQIDQVFISNLPEIVVELLMTLHETADSADSDASQSATALCDFSGDLDPAPNPPYFPSHVIQATFAYI SNCHKTKFKSILEILSKIPDSYQKILLAICEQAAETNNVFKKHRILKIYHLFVSLLLKDIQSGLGGAWAF VLRDVIYTLIHYINKRSSHFTDVSLRSFSLCCDLLSRVCHTAVTQCKDALESHLHVIVGTLIPLVDYQEV QEQVLDLLKYLVIDNKDNKNLSVTIKLLDPFPDHVIFKDLRLTQQKIKYSGGPFSLLEEINHFLSVSAYN PLPLTRLEGLKDLRRQLEQHKDQMLDLLRASQDNPQDGIVVKLVVSLLQLSKMAVNQTGEREVLEAVGRC LGEIGPLDFSTIAVQHNKDVSYTKAYGLPEDRELQWTLIMLTALNNTLVEDSVKIRSAAATCLKNILATK IGHIFWENYKTSADPMLTYLQPFRTSRKKFLEVPRSVKEDVLEGLDAVNLWVPQSESHDIWIKTLTCAFL DSGGINSEILQLLKPMCEVKTDFCQMLLPYLIHDVLLQDTHESWRTLLSAHVRGFFTSCFKHSSQASRSA TPANSDSESENFLRCCLDKKSQRTMLAVVDYLRRQKRPSSGTAFDDAFWLDLNYLEVAKVAQSCSAHFTA LLYAEIYSDKKSTDEQEKRSPTFEEGSQGTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGG KMLQPLTRIRTYEHEATWEKALVTYDLETSISSSTRQSGIIQALQNLGLSHILSVYLKGLDYERREWCAE LQELRYQAAWRNMQWGLCASAGQEVEGTSYHESLYNALQCLRNREFSTFYESLRYASLFRVKEVEELSKG SLESVYSLYPTLSRLQAIGELENSGELFSRSVTDRERSEAYWKWQKHSQLLKDSDFSFQEPLMALRTVIL ETLVQKEMERSQGACSKDILTKHLVEFSVLARTFKNTQLPERAIFKIKQYNSAICGISEWHLEEAQVFWA KKEQSLALSILKQMIKKLDSSFKDKENDAGLKVIYAECLRVCGSWLAETCLENPAVIMQTYLEKAVKVAG SYDGNSRELRNGQMKAFLSLARFSDTQYQRIENYMKSSEFENKQTLLKRAKEEVGLLREHKIQTNRYTVK VQRELELDECALRALREDRKRFLCKAVENYINCLLSGEEHDLWVFRLCSLWLENSGVSEVNGMMKKDGMK ISSYKFLPLMYQLAARMGTKMTGGLGFHEVLNNLISRISLDHPHHTLFIILALANANKDEFLSKPETTRR SRITKSTSKENSHLDEDRTEAATRIIHSIRSKRCKMVKDMEALCDAYIILANMDASQWRAQRKGINIPAN QPITKLKNLEDVVVPTMEIKVDPTGEYENLVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRD DLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRR YRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSS IVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRC CEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESDLHSTPNADDQECKQSLSDTDQ SFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007499 |
| ORF Size | 9198 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007499.2, NP_031525.2 |
| RefSeq Size | 11964 bp |
| RefSeq ORF | 9192 bp |
| Locus ID | 11920 |
| UniProt ID | Q62388 |
| Gene Summary | Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9, UBQLN4 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.[UniProtKB/Swiss-Prot Function] |
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