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Rif1 (NM_175238) Mouse Tagged ORF Clone
CAT＃: MG223410
- TrueORF®
Rif1 (tGFP-tagged) - Mouse Rap1 interacting factor 1 homolog (yeast) (Rif1), (10ug)
ORF Plasmid: DDK
"NM_175238" in other vectors (2)
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CNY 26,700.00
货期*
9周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | 5730435J01Rik; 6530403D07Rik; AU016181; AW549474; D2Ertd145e |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG223410 representing NM_175238
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACGGCCCCAGGTCGCAGCCCCCTGGAGCCGCTTCTGGAGACTTGGGAAGACCCCTCGGTGCCTCCGG GAGAGCAGACGGACGCCTACCTAACTCTGACCAGTCGTATGACTGGAGAAGAAGGAAAAGAAGTCATTGC AGAAATCGAGAAAAACCTTTCTCGGCTGTACACGGTTTTAAAGGCTCACATTTCCAGTCAGAACTCAGAA CTGAGCAGTGCTGCTTTGCAAGCCTTGGGATTTTGTTTATATAATCCCAGAATTACCTCAGGATTGTCAG AGGCAAATATTCAAGAACTGCTTTTAACCTTGAATGGTATCATTAAGAGTTCAGACAAAAATGTGTGTAC CAGGGCACTGTGGGTAATATCCAAACAGACGTTTCCTGCTGAACTTGTTAGCAAAATGGTATCCAGTATT ATTGATTCATTGGAAGTGATACTAAGTAAAGGAGAGATACATTCTGCTGTTGTTGATTTTGAAGCATTAA ATGTTATTATAAGTCATTGGTTTCTTCATTGTAGGCTAATTGAACAAGCCCCAGTTCAAATGGGAGAAGA GTCTGTGAGGTGGGCCAAATTGGTCATACCATTAGTTGTTCACTCAGCACAAAAAGTACATTTGCGGGGA GCCACTGCTCTAGAGATGGGGATGCCATTGCTGCTTCAGAAACAACAAGAAATAGCCTTGATTACAGAGC ACCTTATGACTACTAAATTAATCTCAGAACTCCAAAAACTATTTAAGAATAAAAATGAGACTTATGTGTT AAAACTATGGCCTTTGTTTGTCAAACTTCTTGGAAAGACCTTGCACCGAAGTGGGAGTTTCATCAACTCT TTGTTACAGCTGGAAGAACTGGGCTTCCGTAGTGGAACACCCATGATTAAAAAAATCGCTTTCATTGCTT GGAAAAGCTTAATAGATAATTTTGCTTTAAACCCAGATATACTTTGTAGTGCAAAAAGACTGAAGTTGTT AATGCAACCCTTGAGTTCCATCCATGTGAGAACAGAAACTTTAGCATTAACAAAACTAGAAGTCTGGTGG TATTTACTGATGAGACTTGGACCTCAGCTCCCTGCCAATTTTGAACAGGTGTGCGTGCCACTGATTCAGA GTACAATAAGTGTTGATAGTATTCCTTCACCTCAAGGCAATTCATCTCGAGGGTCTGCTTCTCCAGGCTT AAGTCCACTGACTCCGGGACATAAAGGTGCTTCTCCTTATGGAAGTCCCCGTGGGAACCTGAGTTCAAAT ACAGGTGGAATGGCTGCAATCCCTTCTATTCAGCTTTTGGGACTGGAAATGATGCTTCATTTTTTGTTGG GCCCAGAAGTTTTGAGTTTTGCCAAGCAACACAAGATTGTATTGAGTTTAGAGCCACTGGAACACCCGCT AATCAGCAGCCCTTCTTTCTTCTCCAAGTATGCGCATACACTTATCACTGCTGTTCATGATAGCTTTGTC TCAGTTGGAAAGGATGCCTCAGATGCAGTAGTCAGTGCTATCTGGAAGGAGCTAATTAGCTTGGTGAAGT CAGTTACTGAAGCAGGAAACAGAAAAGAAAAATCAGGTTCTGAAGTTTTGACCCTTCTACTAAAATCTTT GGAAAACATAGTGAAGTCAGAAGTATTTCCTGTATCAAAAACACTGGTTCTCATGGAAATTACAGTTAAA GGACTTCCTCCGAAAGTACTAGGTTCACCAGCATATCAGGTTGCTAATATGGATATTCTTAATGGAACTC CAGCATTGTTTTTAATCCAGTTAATTTTCAACAACAATCTTTTAGAATGTGGTGTAGAAGATGAGAAGTT TTTTCTCAATCTAGAAACACTTGTAGGCTGTGTACTTTCTGGTCCAACATCACCACTGGCTTTTAGTGAT TCTGTTCTAACTGTGATTAATCAGAATGCAAAGCAGTTGGTAAACAAGGAGCATCTCTGGAGAATGTGGA GTATGATAGTCAGTCCACTGACTGATGTGATTCACCAGACCAATGAAGTGAATCAAGGCGATGCCTTAGA ACATAATTTTAGTGCCATCTATGGTGCATTGACTTTACCAATAAACCATATTTTTTCAGCTCAGACATTT CCCACGGGTACCATGAAAGCTTTACTTAAAACTTGGTCAGAATTGTATAGAGCATTTACTCGCTGTGCTT CTTTGGTGGCAACAGCAGAAGAGAATCTGTGCTGTGAAGAACTTTCTTCTAAAATAATGTGCAGTTTGGA AGATGAAGTCCTTTCAGATTTGCTATTCTTGGACAGGATCTCTCATATTATTATTGTAATGGTTGATTGT ATCGACTTTTCACCATATAATAAGAAATACCAGCCAAAAATCAAATCACCGCAGAGATCTTCAGATTGGT CCAGAAAGAAGAAGGAGCCTCTAGGGAAATTGGCTTCTTTATTTAAGCTAATTGTGAAAGTCATCGATAC TTTCCACACTCTAAGCCTCAAGGAAACATTCTCTGATACACTGCTTGCTATTGGTAACTCTATCATTAGC ATGCTTTCCAATGTATTTGGACATATTTCCTTGCCCTCTATGATCCGAGAAATATTTGCAACTTTTACAA GACCTCTGGCTTTACTGTATGAAAACTCAAAGCTGGATGAGGCTCCTAAAGTGTATACTAGTCTGAACAA CAAGTTAGAAAAGCTATTGGGAGAAATTGTTGCATGCCTACAGTTCAGCTATCTTGGAGCCTATGACAGT GAACTTCTTGAACATCTTTCTCCACTCCTGTGCGTAATATTTCTTCACAAGAATAAACAGATTCGGAAAC AGAGTGCTCTGTTGTGGAATGCCACATTTGCTAAAGCGACAGCTCTGGTTTATCCTGAGGAATTAAAACC AATATTAAGACAAGCCAAACAGAAAATTTTGCTTCTGCTGCCTGGTTTGGAAAATGTTGAAATGATGGAT GAGTCCAGTGAACCGTATTCAGAATCAACAGAGAATTCACAATTAAATGTCAAGATAAGTGGCATGGAAA GAAAATCAAGTGGAAAAAGAGATTCCATTTTGGCACATACAAAGGATAAAAAAAAAAAAGTGAAACTGTC GGCCAAACTGAAACTAGAATCTTCATCTCCAAAAATAAAGAGTGGTAAGCTTTTGGAAGAGGAAAAGTCT ACCGACTTTGTCTTCATTCCTCCAGAAGGAAAAGAGACAAAGGCAAGGGTTCTAACTGAGCATCAGAAAG AAGTACTCAAAACAAAACGGTGTGATATTCCTGCCTTGTATAATAATCTGGATGCTTCACAGGACACTTT ATTTTCTGCTCAGTTTAGTCAAGAAGAATCAATGGAAAGCCTCACTTTAACTGAAAAACCAAAAGAAGAT GCCAAGATAATTAAGGAAGAGCAAATGGAAAGTACTATTTTCATCCATCAAGATGCCCCGGAGAACTGTG GAATAGATGAACATTCTGAGAATGCTTCTTTACCAAATTGTGGTGGCTCTGTTGCTGAAACCAATCCAGA AACATTGATCACTGGTTTTGATGCTAGAAAAGAAGTATTAATTTCATCAAAGATATTGTCTGCTGAAAGT TCATCTAGTACAGAAACTTCGGTGGTCAGCAGTAGTTCAGTTTCTAATGCCACTTTTTCTGGAACTCCTC CACAGCCTACAAGTCGGAGACAAACCTTTATTACTTTGGAGAAATTTGATGGCTCAGAAACTAGACCTTT TAGTCCATCCCCCTTGAATAACATATCTTCCACTGTTACAGTGAGAAATAACCAGGATAACACAACTAAC ACTGACATGCCACCAAAAGCAAGGAAAAGAGAAGTGACGAACTCAAAATCTGATTCAGAAAATTTAGCGA ATGCAGGTAAGAAATCAAGTCGGAGATGGAGTAAAGCTGAGCAGTCAGTTACTAAAAAGTCTAAGCCATC ACTGACATCTGAACAGGAAGAGCACTCATCCGAAAATAACTCTCCTGATCTGCTCAGCCCAACAGAACAT GTGTCAGAAAATGATGATCATCCTTCTGAAGCTACCCTAGAGCATAAAGATGGAGATCCTAAACCAGCAG TAGAAAATGCTTCATTGGAAGACTTAACAACAGAAGAGAAAAATGTAGGCATTAATATGGAATCTAAAGA AAGTACAGCCTCAGTTGTAGCACGAACAGAACAAATAGTAAATGAAGATAGTCAGGCTGCTGCACTAGCC CCAAATCCAAAAACACTCCGACGGTCTTCGAGGCGGCGTTCAGAAGCTGTAGATTCTTGCAGTGACAGCC AAGAGAGAGAGAGTGGTCAGCAAAAAAAGGAAAGACGAAAGGAAGAAGAAAAAATAATCTCCAAGAGTCC GTTGCGTATCAAAGATGATAAGTTGCCCACGCAAAAACTAACTGATGAGTCACCTATACAGGAAAATTTA ACTGAAAAGGGAAATACTTTACCTGAGAGAACTTCAGGGGAACCCAGTGTTAATGCTGAAATTGACCAAA ATAGAAGAAAACCAGACCTTGAGAATGTTAGTTCTGAAGGAGGTGGTGGTACCCTGGACAATCTAGACAA GTCGTCTGAGAAACCTTTAAGAGGACGGACACGTTATCAAACAAGAAGAGCTTCGCAGGGTTTGATTTCT GCTGTTGAAAACTCAGAATCTGACAGTTCTGAGGCAAAGGAAGAAGTTTCTAGAAAGAAACGATCAGGGA AATGGAAAAATAGAAGCAGTGACAGTGTTGACATTGAAGAACAAGAAGAAAAAAAGGCTGAAGAGGAAGT TATGAAAACTGCAAATCAGACACTCGATGGCCAGGCAGTTCCTGATGTTGATGTAAATGCAGCGGCTCAG GTTTGTGAAAAAAGTACAAATAACAACAGGGTCATCCTCCAGGATTCTGCTGGGCCTGCAGATTCACTGC AAGCTCCACCCAAAGGCGAGGAGAAAAGTAAGATTAACAAATGTGTAGACAGTTCATTTGTAAGTCTACC TGTGCCAGAGTCAAACCTCAGGACTAGGAATGCCAGTAAGAGATTATTATATAAACAAGATAATGATAGT AATGTGAGGGTATCAGACAGCTCTCTGTCTCCCGAAAAATTCACCCAAGTTGAATGCCAACACAAGAGAA GTAGGAGAGTCAGGAGATCTAAAAGTTGTGACTGCTGTGGCGAAAAATCACAGTCCCAGGAAAAGTCATT TATTGGGTTAAAGAACACAGAAAGTTATGCTATAAAGAGTGTGGAGAAAAAAAAGACAGATCTACAAGTA CCTGAGACTGCCCCTGAAACTCGTGAAGCTCGTGACCATGCTGAAACAAAGTTGGCAGGCGAAGAGCCTC TTGTGAATTTTCATGTGGGTCTTAAAGAAGAGAATTGTACTACTGGTGATTCAGTTAAGTCTGAGGCTGA GTTGCAAGAAGCTTCCCTTCCACCTGAAATAGTAACTGTGAAAGAGAAGACTTACGATACAGACGCTAGT GAAGCAGTGTCTGAAATCCAAGGGCCATGTAGTGAGAACCACAGCCCTGCTGAGGACCCAGGCTTAAGTG AGTGCAAAGACATTTCACAGAAGCAGCTTTCAGAGAACGGAGAGCTTGACATCAGCGATGTAGGGAAGGC ATGCAAAGTCATAGCTGGGTCCAGTCCAGAGGGAGTTGAAACTATGGAATTAAATGTAAGAAATGATGCA TTTGTAGCTGCTGACTCTGAAAAGAGTACCCAAATGGATGTTTCTGTAGATGTGGCAACAGAGGAAGATA ATAAAAAAGATGAATGTGAAGCAGTCACAACTGAAGTGAATGTTGAAGGAGTAGCCACTGAGGACTTTAA TTCAGGTATGGATCTTTCTGATACTCCCATACCTGTAAGCAAGGATGTTGAGACTGAGCACGCAGCTAGT GGGGAAATAGAGGGGGAGAGCAATGAATCTGATTCAGGCTCATGTGAGGAAATGAACAAAGAAATGGGAA GTCACAAAGCCCAGATGAGCACTGAAATTGACAGTGCCAGGGTAAAGGAGACGGACATACTTGCCAGTGC CTCTAAATCTGAAGAAGCGCTGATTGGAAGACTAGACGTCAACACCCAGAGCTTTGTTAGTGACATTGAA ATGAGTTCTGGAGAAAGAACTGTTAATTGCAAAACTGAGACATCCATTGAACTTAATAAATTAGATGAAG CAAAATTAAGTGGCAATGAAGCTACAGTGGGAAATGATACTCTGCAGGAAGTTTGCTTTACTTCAGAGAA AGTGGAGAAATTACCACAGTGTCTGCTAGTTCAAGTGGCTTCTGAACTTGGAGCAGAAAGCAATACTACG TCTCCCGAAAAGTTAGAGCTGGATTCTTTTGGATCAGTAAATGAAAGTCCTAGTGGTATGCAGCAGGCAC GTTGTGTCTGGTCACCTTTGGCTTCTCCATCCACAAGCATTTTAAAGAGAGGACTAAAAAGATCCCAAGA AGATGAGATCTCACCAGTTAACAAGATTAGACGTGTCTCGTTTGCAGATCCAATATACCAAGCAGGATTG GCAGATGACATTGATAGGCGTTGCTCTGTTGTTAGATCTCATTCTTCAAATAGCTCTCCCATAATAAAAA GTGTTAAAACTTCACCTACTTCACACTCTAAGCATAATACCACTTCAGCCAAAGGATTTCTGTCCCCAGG ATCACAGAGCTCTAAATTTAAGAGCCCAAAGAAGTGTTTAATTACAGAAATGGCCCAAGAATCCATGCTG TCCCCAACAGAAAGTGTTTACCCAGCTTTGGTGAACTGTGCAGCATCAGTTGACATCATTTTACCTCAGA TTACATCAAATATGTGGGCAAGAGGTCTTGGGCAACTCATCAGAGCCAAGAATATAAAAACCATTGGGGA TTTGAGTACGCTTACGGCATCTGAAATAAAAACTCTGCCTATCCGTTCTCCAAAGGTGTTTAATGTAAAA AAGGCCCTCAGAGTATACCATGAGCAACAGATGAAATCTCGTGGACTTGAAGAAATTCCAATTTTTGATA TTTCTGAGAAGGCAGTAAATGGAGTGGAGAGCAGGACTGTCTCCACGGATGAAGAAAGGTTCGCCTCAGA TTTGATTGAACCTGTGACCCTAGATACCCCATTGTCTAAAAATCTTGTGGCACAAATTAGTGCTCTTGCT CTTCAACTGGACTCAGAAGATCTCTACAGTTACACTGGAAGCCAGCTATTTGAAATGCATGAAAAACTTG GTACCATGGCAAACTCTATAATAAGAAATCTACAGTCACGTTGGAGATCACCAGCCCATGAAAATTCT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG223410 representing NM_175238
Red=Cloning site Green=Tags(s) MTAPGRSPLEPLLETWEDPSVPPGEQTDAYLTLTSRMTGEEGKEVIAEIEKNLSRLYTVLKAHISSQNSE LSSAALQALGFCLYNPRITSGLSEANIQELLLTLNGIIKSSDKNVCTRALWVISKQTFPAELVSKMVSSI IDSLEVILSKGEIHSAVVDFEALNVIISHWFLHCRLIEQAPVQMGEESVRWAKLVIPLVVHSAQKVHLRG ATALEMGMPLLLQKQQEIALITEHLMTTKLISELQKLFKNKNETYVLKLWPLFVKLLGKTLHRSGSFINS LLQLEELGFRSGTPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWW YLLMRLGPQLPANFEQVCVPLIQSTISVDSIPSPQGNSSRGSASPGLSPLTPGHKGASPYGSPRGNLSSN TGGMAAIPSIQLLGLEMMLHFLLGPEVLSFAKQHKIVLSLEPLEHPLISSPSFFSKYAHTLITAVHDSFV SVGKDASDAVVSAIWKELISLVKSVTEAGNRKEKSGSEVLTLLLKSLENIVKSEVFPVSKTLVLMEITVK GLPPKVLGSPAYQVANMDILNGTPALFLIQLIFNNNLLECGVEDEKFFLNLETLVGCVLSGPTSPLAFSD SVLTVINQNAKQLVNKEHLWRMWSMIVSPLTDVIHQTNEVNQGDALEHNFSAIYGALTLPINHIFSAQTF PTGTMKALLKTWSELYRAFTRCASLVATAEENLCCEELSSKIMCSLEDEVLSDLLFLDRISHIIIVMVDC IDFSPYNKKYQPKIKSPQRSSDWSRKKKEPLGKLASLFKLIVKVIDTFHTLSLKETFSDTLLAIGNSIIS MLSNVFGHISLPSMIREIFATFTRPLALLYENSKLDEAPKVYTSLNNKLEKLLGEIVACLQFSYLGAYDS ELLEHLSPLLCVIFLHKNKQIRKQSALLWNATFAKATALVYPEELKPILRQAKQKILLLLPGLENVEMMD ESSEPYSESTENSQLNVKISGMERKSSGKRDSILAHTKDKKKKVKLSAKLKLESSSPKIKSGKLLEEEKS TDFVFIPPEGKETKARVLTEHQKEVLKTKRCDIPALYNNLDASQDTLFSAQFSQEESMESLTLTEKPKED AKIIKEEQMESTIFIHQDAPENCGIDEHSENASLPNCGGSVAETNPETLITGFDARKEVLISSKILSAES SSSTETSVVSSSSVSNATFSGTPPQPTSRRQTFITLEKFDGSETRPFSPSPLNNISSTVTVRNNQDNTTN TDMPPKARKREVTNSKSDSENLANAGKKSSRRWSKAEQSVTKKSKPSLTSEQEEHSSENNSPDLLSPTEH VSENDDHPSEATLEHKDGDPKPAVENASLEDLTTEEKNVGINMESKESTASVVARTEQIVNEDSQAAALA PNPKTLRRSSRRRSEAVDSCSDSQERESGQQKKERRKEEEKIISKSPLRIKDDKLPTQKLTDESPIQENL TEKGNTLPERTSGEPSVNAEIDQNRRKPDLENVSSEGGGGTLDNLDKSSEKPLRGRTRYQTRRASQGLIS AVENSESDSSEAKEEVSRKKRSGKWKNRSSDSVDIEEQEEKKAEEEVMKTANQTLDGQAVPDVDVNAAAQ VCEKSTNNNRVILQDSAGPADSLQAPPKGEEKSKINKCVDSSFVSLPVPESNLRTRNASKRLLYKQDNDS NVRVSDSSLSPEKFTQVECQHKRSRRVRRSKSCDCCGEKSQSQEKSFIGLKNTESYAIKSVEKKKTDLQV PETAPETREARDHAETKLAGEEPLVNFHVGLKEENCTTGDSVKSEAELQEASLPPEIVTVKEKTYDTDAS EAVSEIQGPCSENHSPAEDPGLSECKDISQKQLSENGELDISDVGKACKVIAGSSPEGVETMELNVRNDA FVAADSEKSTQMDVSVDVATEEDNKKDECEAVTTEVNVEGVATEDFNSGMDLSDTPIPVSKDVETEHAAS GEIEGESNESDSGSCEEMNKEMGSHKAQMSTEIDSARVKETDILASASKSEEALIGRLDVNTQSFVSDIE MSSGERTVNCKTETSIELNKLDEAKLSGNEATVGNDTLQEVCFTSEKVEKLPQCLLVQVASELGAESNTT SPEKLELDSFGSVNESPSGMQQARCVWSPLASPSTSILKRGLKRSQEDEISPVNKIRRVSFADPIYQAGL ADDIDRRCSVVRSHSSNSSPIIKSVKTSPTSHSKHNTTSAKGFLSPGSQSSKFKSPKKCLITEMAQESML SPTESVYPALVNCAASVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVFNVK KALRVYHEQQMKSRGLEEIPIFDISEKAVNGVESRTVSTDEERFASDLIEPVTLDTPLSKNLVAQISALA LQLDSEDLYSYTGSQLFEMHEKLGTMANSIIRNLQSRWRSPAHENS TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_175238 |
| ORF Size | 7278 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_175238.6 |
| RefSeq Size | 8502 bp |
| RefSeq ORF | 7281 bp |
| Locus ID | 51869 |
| UniProt ID | Q6PR54 |
| Gene Summary | Key regulator of TP53BP1 that plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage: acts by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs (PubMed:23333305, PubMed:23306437, PubMed:23306439). In response to DNA damage, interacts with ATM-phosphorylated TP53BP1 (PubMed:23333305, PubMed:23306437, PubMed:23306439). Interaction with TP53BP1 leads to dissociate the interaction between NUDT16L1/TIRR and TP53BP1, thereby unmasking the tandem Tudor-like domain of TP53BP1 and allowing recruitment to DNA DSBs (By similarity). Once recruited to DSBs, RIF1 and TP53BP1 act by promoting NHEJ-mediated repair of DSBs (PubMed:23333305, PubMed:23306437). In the same time, RIF1 and TP53BP1 specifically counteract the function of BRCA1 by blocking DSBs resection via homologous recombination (HR) during G1 phase (PubMed:23333305, PubMed:23306437). Also required for immunoglobulin class-switch recombination (CSR) during antibody genesis, a process that involves the generation of DNA DSBs (PubMed:23333305, PubMed:23333306, PubMed:23306439). Promotes NHEJ of dysfunctional telomeres (PubMed:23333305).[UniProtKB/Swiss-Prot Function] |
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