United States
Germany
Japan
United Kingdom
China
Fam89b (NM_023166) Mouse Untagged Clone
CAT＃: MC205091
Fam89b (untagged) - Mouse family with sequence similarity 89, member B (Fam89b), transcript variant 2, (10ug)
CNY 2,000.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1110021A21Rik; MMTV; Mtvr2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC056166
GGCCTGCGGGCGGTGGCTGAGATCTCTCCGGAGACCGGGCCACGGAGAGCTGGTTCTCTGGGCAACAGCC CGCTGAAAACGTAAGAGGGGTCCAGGCGGCATCGTGGTCCACGCCTGCCTGGCTATGAACGGGCTGCCCG CGACTGAGGCGCCGGGCGGCGCGGGCTGCGCTCTGGCCGGGCTCCCGCCGCTACCGCGCGGCCTCAGCGG CCTTCTTAACGCTAGTGGGGGCTCGTGGAGGGAGCTGGAGCGTGTCTACAGCCAACGGAGCCGCATCCAC GACGAACTGAGTCGTGCCGCCCGCGCCCCGGATGGTCCTCGCCATGCCGCTGGATCTGCTAACTCAGGTT CTGCAGCGGGCCCGCGCCGCCCGGTTAACCTCGACTCTGCACTAGCCGCGCTGCGCAAGGAGATGCTGTG GGGCCTGTACGAGTCGATCCAGGACTACAAGCATCTGTGCCAAGACCTGAGCTTGTGCCAGGACCTGTCA TCCTCTCTGCACTCGGACAGCTCCTACCCACCTGATGCCGGCCTGTCTGATGACGAGGAGCCTCCTGATG CCAGCCTGCCCCCAGACCCTCCACCCCTCACCGTACCCCAGACTCACAATGCCCGTGACCAGTGGTTGCA GGATGCTTTCCAAATCAGCCTTTGAAAGCTGAGGTGGATAGGAACGCACCCATACAAAAGGCTCAAAACT TGCCCTTCAGCAAGTCCTTAGTCTACAGTGCCTGCTCTTTTACCGGTACCACCTCACCTCACTTCAGGAG GGCAAGGCATTATACCCATCAGGCAAAGCGGTCAAGATTGCAGCCTGTGCCCAGTGTCCTGGGCTTCCAC TTCTCCCACATGTGTGCACCCTAGCTTGGCCAGCCCTTAGTCTGACTGTGGGGCCCAAAGCGTCTTGCAC TCCCGTTTGCATCTCTGGGACTGGGATGAGTGCCTAGCTCTCATCTCTTTTTCGTCTTTTGCTGCCTCTT GCAGCTGCTGGCTCAGCGGCATCCCTACCAGTGGCCCCAGGGGTTCATTGCCTGGGACAAGGGCTCCAGA ACCCACCTCTGTAGCCACCCACGACCAGAAAGGCTAAGGTCTTTATGCTGGATATTTAAGTTTAGCGGCC AGTTCCTGGGCGGGAAAATAAATAATTTCAGCATTGTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_023166 |
| Insert Size | 531 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC056166, AAH56166 |
| RefSeq Size | 1175 bp |
| RefSeq ORF | 531 bp |
| Locus ID | 17826 |
| Gene Summary | Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta (PubMed:12646588). Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (PubMed:25107909).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG201546 | Fam89b (tGFP-tagged) - Mouse mammary tumor virus receptor 2 (Mtvr2), transcript variant 2 |
CNY 2,850.00 |
|
| MR201546 | Fam89b (Myc-DDK-tagged) - Mouse family with sequence similarity 89, member B (Fam89b), transcript variant 2 |
CNY 2,400.00 |
|
| MR201546L3 | Lenti ORF clone of Fam89b (Myc-DDK-tagged) - Mouse family with sequence similarity 89, member B (Fam89b), transcript variant 2 |
CNY 4,750.00 |
|
| MR201546L4 | Lenti ORF clone of Fam89b (mGFP-tagged) - Mouse family with sequence similarity 89, member B (Fam89b), transcript variant 2 |
CNY 4,750.00 |
