Nkx2.2 (NKX2-2) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central region (between 98-128aa) of human NKX2-2
Specificity	This antibody recognizes human NKX2-2.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	NK2 homeobox 2
Database Link	Entrez Gene 4821 Human UniProt ID O95096
Background	The protein encoded by the NKX2-2 gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. The NKX2-2 gene is found on chromosome 20 near NKX2-4 and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Synonyms	NKX2.2, NKX2B
Note	Molecular Weight: 30133 Da
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Maturity onset diabetes of the young

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