GUCY2C (248-262) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/100-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Human intestinal Guanylate Cyclase (aa 248-262) polyLysine-conjugated
Specificity	This antibody detects synthetic intestinal Guanylate Cyclase (aa 248-262).
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	guanylate cyclase 2C
Database Link	Entrez Gene 2984 Human UniProt ID P25092
Background	Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.
Synonyms	Heat-stable enterotoxin receptor, hSTAR, GUC2C, STAR, Guanylyl cyclase C, Intestinal guanylate cyclase, GC-C
Reference Data

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