Carboxypeptidase H (CPE) (NM_001873) Human Recombinant Protein
CAT#: TP721092M
Purified recombinant protein of Human carboxypeptidase E (CPE)
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CNY 7,220.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Arg42-Ser453
|
Tag | C-His |
Predicted MW | 47.1 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Storage | Store at -80°C. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_001864 |
Locus ID | 1363 |
UniProt ID | P16870, A0A384N679 |
Refseq Size | 2443 |
Cytogenetics | 4q32.3 |
Refseq ORF | 1428 |
Synonyms | CPH; IDDHH |
Summary | This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015] |
Protein Families | Druggable Genome, Protease, Secreted Protein |
Protein Pathways | Type I diabetes mellitus |
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