AP3S2 (NM_005829) Human Mass Spec Standard

Specifications

Product Data
Description	AP3S2 MS Standard C13 and N15-labeled recombinant protein (NP_005820)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201104
Predicted MW	22 kDa
Protein Sequence	Sequence Link (showhide) >RC201104 protein sequence Red=Cloning site Green=Tags(s) MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYAT LYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQ IEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005820
RefSeq Size	5934
RefSeq ORF	579
Synonyms	AP3S3; sigma3b
Locus ID	10239
Cytogenetics	15q26.1
Summary	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[UniProtKB/Swiss-Prot Function]
Protein Pathways	Lysosome

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