Apc11 (ANAPC11) (NM_001002244) Human Mass Spec Standard

CAT#: PH300097

ANAPC11 MS Standard C13 and N15-labeled recombinant protein (NP_001002244)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ANAPC11 MS Standard C13 and N15-labeled recombinant protein (NP_001002244)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200097
Predicted MW 20.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001002244
RefSeq Size 1186
RefSeq ORF 588
Synonyms APC11; Apc11p; HSPC214
Locus ID 51529
Cytogenetics 17q25.3
Summary Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
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