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DOPA Decarboxylase (DDC) (NM_001082971) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC219037L1V
- LentiORF®
-
Lenti ORF particles, DDC (Myc-DDK tagged) - Human dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | DOPA Decarboxylase (DDC) (NM_001082971) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AADC |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001082971 |
| ORF Size | 1440 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC219037).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001082971.1, NP_001076440.1 |
| RefSeq Size | 2090 bp |
| RefSeq ORF | 1443 bp |
| Locus ID | 1644 |
| Protein Families | Druggable Genome |
| Protein Pathways | Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism |
| MW | 53.9 kDa |
| Gene Summary | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011] |
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