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Cyclin E2 (CCNE2) (NM_057749) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC218597L1V
- LentiORF®
-
Lenti ORF particles, CCNE2 (Myc-DDK tagged) - Human cyclin E2 (CCNE2), 200ul, >10^7 TU/mL
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CNY 8,455.00
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Specifications
| Product Data | |
| Product Name | Cyclin E2 (CCNE2) (NM_057749) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CYCE2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_057749 |
| ORF Size | 1212 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218597).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_057749.1 |
| RefSeq Size | 2748 bp |
| RefSeq ORF | 1215 bp |
| Locus ID | 9134 |
| Domains | cyclin_C, CYCLIN, cyclin |
| Protein Families | Druggable Genome |
| Protein Pathways | Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer |
| MW | 46.6 kDa |
| Gene Summary | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008] |
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