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SP1 (NM_138473) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209154L1V
- LentiORF®
-
Lenti ORF particles, SP1 (Myc-DDK tagged) - Human Sp1 transcription factor (SP1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 2 publications. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | SP1 (NM_138473) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_138473 |
| ORF Size | 2355 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209154).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_138473.2 |
| RefSeq Size | 7667 bp |
| RefSeq ORF | 2358 bp |
| Locus ID | 6667 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Huntington's disease, TGF-beta signaling pathway |
| MW | 80.7 kDa |
| Gene Summary | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
SP1 regulates KLF4 via SP1 binding motif governed by DNA methylation during odontoblastic differentiation of human dental pulp cells.
,null,
Journal of cellular biochemistry
,PubMed ID 31009133
[SP1]
|
|
The Cyclin-dependent Kinase Inhibitor p16INK4a Physically Interacts with Transcription Factor Sp1 and Cyclin-dependent Kinase 4 to Transactivate MicroRNA-141 and MicroRNA-146b-5p Spontaneously and in Response to Ultraviolet Light-induced DNA Damage *
,null,
The Journal of Biological Chemistry
,PubMed ID 24163379
[SP1]
|
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