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CLC7 (CLCN7) (NM_001287) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203450L4V
- LentiORF®
-
Lenti ORF particles, CLCN7 (mGFP-tagged) - Human chloride channel 7 (CLCN7), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | CLC7 (CLCN7) (NM_001287) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CLC-7; CLC7; HOD; OPTA2; OPTB4; PPP1R63 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001287 |
| ORF Size | 2415 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203450).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001287.3 |
| RefSeq Size | 4236 bp |
| RefSeq ORF | 2418 bp |
| Locus ID | 1186 |
| Domains | CBS, voltage_CLC |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| MW | 88.7 kDa |
| Gene Summary | The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008] |
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