NR2C2 (NM_001291694) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	TAK1; TR4
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >SC336925 representing NM_001291694. Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACCAGCCCCTCCCCACGCATCCAGATAATCTCCACCGACTCTGCTGTAGCCTCACCTCAGCGCATT CAGATTGTCACAGACCAGCAGACAGGACAGAAAATCCAGATAGTCACCGCAGTGGACGCCTCCGGATCC CCCAAACAGCAGTTCATCCTGACCAGCCCAGATGGAGCTGGAACTGGGAAGGTGATCCTGGCTTCCCCA GAGACATCCAGCGCCAAGCAACTCATATTCACCACCTCAGACAACCTCGTCCCTGGCAGGATCCAGATT GTCACGGATTCTGCCTCTGTGGAGCGTTTACTGGGGAAGACGGACGTCCAGCGGCCCCAGGTGGTAGAG TACTGTGTGGTCTGTGGCGACAAAGCCTCCGGCCGTCACTATGGGGCTGTCAGTTGTGAAGGTTGCAAA GGTTTCTTCAAAAGGAGTGTGAGGAAAAATTTGACCTACAGCTGCCGGAGCAACCAAGACTGCATCATC AATAAACATCACCGGAACCGCTGTCAGTTTTGCCGGCTGAAAAAATGCTTAGAGATGGGCATGAAAATG GAATCTGTGCAGAGTGAACGGAAGCCCTTCGATGTGCAACGGGAGAAACCAAGCAATTGTGCTGCTTCA ACTGAGAAAATCTATATCCGGAAAGACCTGAGAAGTCCCCTGATAGCTACTCCCACGTTTGTGGCAGAC AAAGATGGAGCAAGACAAACAGGTCTTCTTGATCCAGGGATGCTTGTGAACATCCAGCAGCCTTTGATA CGTGAGGATGGTACAGTTCTCCTGGCCACGGATTCTAAGGCTGAAACAAGCCAGGGAGCTCTGGGCACA CTGGCAAATGTAGTGACCTCCCTTGCCAACCTAAGTGAATCTTTGAACAACGGTGACACTTCAGAAATC CAGCCAGAGGACCAGTCTGCAAGTGAGATAACTCGGGCATTTGATACCTTAGCTAAAGCACTTAATACC ACAGACAGCTCCTCTTCTCCAAGCTTGGCAGATGGGATAGACACCAGTGGAGGAGGGAGCATCCACGTC ATCAGCAGAGACCAGTCGACACCCATCATTGAGGTTGAAGGCCCCCTCCTTTCAGACACACACGTCACA TTTAAGCTAACAATGCCCAGTCCAATGCCAGAGTACCTCAACGTGCACTACATCTGTGAGTCTGCATCC CGTCTGCTTTTCCTCTCAATGCACTGGGCTCGGTCAATCCCAGCCTTTCAGGCACTTGGGCAGGACTGC AACACCAGCCTTGTGCGGGCCTGCTGGAATGAGCTCTTCACCCTCGGCCTGGCCCAGTGTGCCCAGGTC ATGAGTCTCTCCACCATCCTGGCTGCCATTGTCAACCACCTGCAGAACAGCATCCAGGAAGATAAACTT TCTGGTGACCGGATAAAGCAAGTCATGGAGCACATCTGGAAGCTGCAGGAGTTCTGTAACAGCATGGCG AAGCTGGATATAGATGGCTATGAGTATGCATACCTTAAAGCTATAGTTCTCTTTAGCCCCGATCATCCA GGTTTGACCAGCACAAGCCAGATTGAAAAATTCCAAGAAAAGGCACAGATGGAGTTGCAGGACTATGTT CAGAAAACCTACTCAGAAGACACCTACCGATTGGCCCGGATCCTCGTTCGCCTGCCGGCACTCAGGCTG ATGAGCTCCAACATAACAGAAGAACTTTTTTTTACTGGTCTCATTGGCAATGTTTCGATAGACAGCATA ATCCCCTACATCCTCAAGATGGAGACAGCAGAGTATAATGGCCAGATCACCGGAGCCAGTCTATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites	SgfI-MluI
ACCN	NM_001291694
Insert Size	1791 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001291694.1
RefSeq Size	8428 bp
RefSeq ORF	1791 bp
Locus ID	7182
UniProt ID	P49116
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
MW	65.4 kDa
Gene Summary	This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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