MAP3K13 (NM_001242317) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	LZK; MEKK13; MLK
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC331786 representing NM_001242317. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGTATTGTGGCATTCAAATCCTAGCACTCTGGGAGAGGGGTGTTTGTACTCAGGCCCCATGTTATTGT ATTATCATGGAATACTGTGCCCATGGACAACTCTACGAGGTCTTACGAGCTGGCAGGAAGATCACACCT CGATTGCTAGTAGACTGGTCCACAGGAATTGCAAGTGGAATGAATTATTTGCACCTCCATAAAATTATT CATCGTGATCTCAAATCACCTAATGTTTTAGTGACCCACACAGATGCGGTAAAAATTTCAGATTTTGGT ACATCTAAGGAACTCAGTGACAAAAGTACCAAGATGTCATTTGCTGGCACGGTCGCATGGATGGCGCCA GAGGTGATACGGAATGAACCTGTCTCTGAAAAAGTTGATATATGGTCTTTTGGAGTGGTGCTTTGGGAG CTGCTGACAGGAGAGATCCCTTACAAAGATGTAGATTCTTCAGCCATTATCTGGGGTGTTGGAAGCAAC AGCCTCCACCTTCCAGTTCCTTCCACTTGCCCTGATGGATTCAAAATCCTTATGAAACAGACGTGGCAG AGTAAACCTCGAAACCGACCTTCTTTTCGGCAGACACTCATGCATTTAGACATTGCCTCTGCAGATGTA CTTGCCACCCCACAAGAAACTTACTTCAAGTCTCAGGCTGAATGGAGAGAAGAAGTGAAAAAACATTTT GAGAAGATCAAAAGTGAAGGAACTTGTATACACCGGTTAGATGAAGAACTGATTCGAAGGCGCAGAGAA GAGCTCAGGCATGCGCTGGATATTCGTGAACACTATGAGCGGAAGCTTGAGCGGGCGAATAATTTATAC ATGGAATTGAGTGCCATCATGCTGCAGCTAGAAATGCGGGAGAAGGAGCTCATTAAGCGTGAGCAAGCA GTGGAAAAGAAGTATCCTGGGACCTACAAACGACACCCTGTTCGTCCTATCATCCATCCCAATGCCATG GAGAAACTCATGAAAAGGAAAGGAGTGCCTCACAAATCTGGGATGCAGACCAAACGGCCAGACTTGTTG AGATCAGAAGGGATCCCCACCACAGAAGTGGCTCCCACTGCATCCCCTTTGTCCGGAAGTCCCAAAATG TCCACTTCTAGCAGCAAGAGCCGATATCGAAGCAAACCACGCCACCGCCGAGGGAATAGCAGAGGCAGC CATAGTGACTTTGCCGCAATCTTGAAAAACCAGCCAGCCCAGGAAAATTCACCCCATCCCACTTACCTG CACCAAGCTCAATCCCAATACCCTTCTCTTCATCACCATAATTCTCTGCAGCAGCAATACCAGCAGCCC CCTCCTGCCATGTCCCAGAGTCACCATCCCAGACTCAATATGCACGGACAGGACATAGCAACCTGCGCC AACAACCTGAGGTATTTCGGCCCAGCAGCAGCCCTGCGGAGCCCACTCAGCAACCATGCTCAGAGACAG CTGCCCGGCTCGAGCCCTGACCTCATCTCCACAGCCATGGCTGCAGACTGCTGGAGAAGTTCTGAGCCT GACAAGGGCCAAGCTGGTCCCTGGGGCTGTTGCCAGGCTGACGCTTATGACCCCTGCCTTCAGTGCAGG CCAGAACAGTATGGGTCCTTAGACATACCCTCTGCTGAGCCAGTGGGGAGGAGCCCTGACCTTTCCAAG TCACCAGCACATAATCCTCTCTTGGAAAACGCCCAGAGTTCTGAGAAAACGGAAGAAAATGAATTCAGC GGCTGTAGGTCTGAGTCATCCCTCGGCACCTCTCATCTCGGCACCCCTCCAGCGCTACCTCGAAAAACA AGGCCTCTGCAGAAGAGTGGAGATGACTCCTCAGAAGAGGAAGAAGGGGAAGTAGATAGTGAAGTTGAA TTTCCACGAAGACAGAGGCCCCATCGCTGTATCAGCAGCTGCCAGTCATATTCAACCTTTAGCTCTGAG AATTTCTCTGTGTCTGATGGAGAAGAGGGAAATACCAGTGACCACTCAAACAGTCCTGATGAGTTAGCT GATAAACTTGAAGACCGCTTGGCAGAGAAGCTAGACGACCTGCTGTCCCAGACGCCAGAGATTCCCATT GACATATCCTCACACTCGGATGGGCTCTCTGACAAGGAGTGTGCCGTGCGCCGTGTGAAGACTCAGATG TCTCTGGGCAAGCTGTGTGTGGAGGAACGTGGCTATGAGAACCCCATGCAGTTTGAAGAATCGGACTGT GACTCTTCAGATGGGGAGTGTTCTGATGCCACAGTTAGGACCAATAAACACTACAGCTCTGCTACCTGG TAA
Restriction Sites	SgfI-MluI
ACCN	NM_001242317
Insert Size	2280 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001242317.1
RefSeq Size	9094 bp
RefSeq ORF	2280 bp
Locus ID	9175
UniProt ID	O43283
Protein Families	Druggable Genome, Protein Kinase, Transcription Factors
Protein Pathways	MAPK signaling pathway
MW	85.4 kDa
Gene Summary	The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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