PRPS1 (NM_001204402) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRS-I; PRSI
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC329751 representing NM_001204402. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGTGCTTGTGGGAGATGTGAAGGATCGGGTGGCCATCCTTGTGGATGACATGGCTGACACTTGTGGC ACAATCTGCCATGCAGCTGACAAACTTCTCTCAGCTGGCGCCACCAGAGTTTATGCCATCTTGACTCAT GGAATCTTCTCCGGTCCTGCTATTTCTCGCATCAACAACGCATGCTTTGAGGCAGTAGTAGTCACCAAT ACCATACCTCAGGAGGACAAGATGAAGCATTGCTCCAAAATACAGGTGATTGACATCTCTATGATCCTT GCAGAAGCCATCAGGAGAACTCACAATGGAGAATCCGTTTCTTACCTATTCAGCCATGTCCCTTTATAA
Restriction Sites	SgfI-MluI
ACCN	NM_001204402
Insert Size	345 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001204402.1
RefSeq Size	1748 bp
RefSeq ORF	345 bp
Locus ID	5631
UniProt ID	P60891
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Pentose phosphate pathway, Purine metabolism
MW	12.3 kDa
Gene Summary	This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.