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TESK2 (NM_007170) Human Untagged Clone
CAT＃: SC323613
TESK2 (untagged)-Kinase deficient mutant (K87M) of Human testis-specific kinase 2 (TESK2)
CNY 4,144.00
CNY 9,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_007170, the custom clone sequence may differ by one or more nucleotides
ATGGATCGGAGCAAACGGAATTCAATTGCAGGATTTCCTCCACGTGTGGAGCGTCTTGAAGAGTTTGAAG GAGGTGGTGGAGGAGAAGGAAATGTGAGCCAGGTGGGAAGAGTTTGGCCATCTTCGTATCGAGCTCTTAT AAGTGCCTTTTCCAGACTGACGCGTTTGGATGATTTCACCTGTGAAAAAATAGGGTCTGGCTTCTTTTCT GAAGTGTTCAAGGTACGACACCGAGCTTCTGGTCAGGTGATGGCTCTTAAGATGAACACATTGAGCAGTA ACCGGGCAAACATGCTGAAAGAAGTACAGCTCATGAATAGACTCTCCCATCCCAACATCCTTAGGTTCAT GGGTGTATGTGTTCATCAAGGACAATTGCATGCACTTACAGAGTATATCAACTCCGGGAACCTGGAACAG TTGCTAGACAGTAACCTGCATTTGCCTTGGACTGTGAGGGTAAAACTGGCCTATGACATAGCAGTGGGCC TCAGCTACCTTCACTTCAAAGGCATTTTTCATCGGGACCTCACATCTAAGAACTGCCTGATAAAGAGGGA TGAGAATGGTTACTCTGCAGTGGTAGCTGACTTTGGCCTGGCTGAGAAGATCCCCGATGTCAGCATGGGG AGTGAGAAGCTGGCCGTGGTGGGTTCCCCATTCTGGATGGCACCTGAGGTTCTCCGAGATGAGCCCTATA ATGAAAAGGCAGATGTGTTCTCTTATGGTATCATCCTCTGCGAGATCATCGCCCGCATCCAGGCCGATCC GGACTATCTTCCCCGCACAGAGAATTTCGGGCTGGACTATGATGCTTTCCAGCACATGGTGGGAGACTGT CCCCCAGATTTTCTGCAACTTACTTTCAACTGCTGTAACATGGATCCCAAACTGCGCCCATCTTTTGTGG AGATTGGGAAGACCCTGGAGGAAATTCTGAGCCGCCTACAGGAAGAAGAGCAGGAGAGGGATAGGAAGCT GCAGCCCACAGCCAGGGGACTCTTGGAGAAAGCACCTGGGGTGAAGCGACTAAGCTCACTGGATGACAAG ATCCCCCACAAGTCACCATGCCCAAGACGTACCATCTGGCTGTCTCGAAGCCAGTCAGATATCTTTTCCC GTAAGCCCCCACGTACAGTGAGTGTCTTGGACCCATACTACCGGCCACGAGATGGTGCTGCCCGCACCCC CAAAGTCAACCCTTTTAGTGCTCGCCAGGACCTCATGGGGGGCAAGATCAAGTTTTTTGACCTGCCCAGC AAGTCTGTCATCTCTCTGGTATTTGACCTGGATGCACCAGGGCCCGGAACTATGCCCCTGGCTGACTGGC AGGAGCCCCTGGCCCCACCTATTCGCCGGTGGCGTTCCTTGCCTGGTTCGCCTGAGTTCTTGCATCAAGA GGCTTGTCCATTTGTGGGCCGGGAAGAATCGCTATCTGATGGGCCCCCACCACGCCTAAGTAGTCTCAAG TACAGAGTTAAAGAGATCCCACCATTCCGGGCATCTGCCCTACCAGCTGCTCAAGCCCATGAGGCTATGG ACTGCTCCATTCTCCAGGAAGAAAATGGTTTTGGGTCCAGGCCCCAGGGGACCAGTCCATGCCCTGCGGG TGCTTCTGAGGAGATGGAGGTAGAAGAAAGGCCAGCAGGCTCAACTCCAGCCACCTTCTCCACCTCAGGC ATAGGCCTGCAAACCCAGGGAAAGCAGGATGGGTGA >OriGene 5' read for mutant NM_007170 unedited
CCGCCGTTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAAC CGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGCCCTGTTGGCTTCGC TGGTCGGATCGTCCTCCTGGCCCCGCCAAACAGGCGGGGGGAGCGGCCCCGACTGTGGGGCCATGGCCGT AGTCTCCTCGTTCTCCGCCGCCGCTAGCCTACCTGAGTCTCCGGCTTCTGCGCTAGGGGCTCCTACCGCC TCCGCAGGCTAGGAGCCGCTGCCCCACGAGCTGTGACGGTTACTAGCTCCTCTTGCCGCCGCCCCCCCCT TGCCCCCCCGCCCCGCGGGCTGCTCGTTTGCAAAAGCGACCTAGAAGAATAAGAATTCATAAACTTTTTA AGTGTGGGATTTCCTTCGTAAGCAAAAAAAAAAGTTGATTTATTTAAACCTTGGGATGGAGATCAAAACG GAATTTCATTTGCCGGGATTTCCTCCCCCTTTGAGGACCCTCTTGTGGAAAAATTTAAAGGAGGGGGGGG GGGGAAAAAGAAAATTGCACCCGGGGGGGGAGAAACATTTGAAATTTTTTTTAAAAAGCGGGGCAAAAAG GGGGGCAAAAAAAAAAAACCCCTTTAAAAATTTCTCCCCCAGAAAAAAAGAGGGGCCCCCCCCCCTTTTT TTCACGGGTTCAAAGGGGAAAATCCCCCCCCTCCCCCCGAGGCGGCGGGGTCTTTTTTTTTAAAAAAAAA TAGGGCGGCGGGTGGCGGGGAAACCTGGGGGGAACCACCCCCTGAGCGTGGGGGGGATTTACTCTCCCGA TGTTATAGAGCATGGGGGAGTGTTTTCTTTTCCCAGGAACTCTTTCTCACATGGTTGGTAGTAATCTCAC GCGTGTATCAGAAGAACATATCACCCACCCCTATTTGCGTTGTGCGGAGTAGGGGAGGATATAGTCTACG CTAATATAACTACGCGATCATTCATGTCTCCGTTTCATATTAGCGATATACTCTTATCTGAGAGCCGCTC ACAGCATTCATA >SC323613 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
TCTTCGTAATACGGTCTGGCTTCTTTTCTGAGTGTTCAAGGTACGACACCGAGCTTCTGGTCAGGTGATG GCTCTTATGATGAACACATTGAGCAGTAACCGGGCAAACATGCTGAAAGAAGTACAGCTCATGAATAGAC TCTCCCATCCCAACATCCTTAGGTTCATGGGTGTATGTGTTCATCAAGGACAATTGCATGCACTTACAGA GTATATCAACTCCGGGAACCTGGAACAGTTGCTAGACAGTAACCT |
| Restriction Sites | Please inquire |
| ACCN | NM_007170 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007170.1, NP_009101.1 |
| RefSeq Size | 3016 bp |
| RefSeq ORF | 1668 bp |
| Locus ID | 10420 |
| UniProt ID | Q96S53 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224117 | TESK2 (Myc-DDK-tagged)-Human testis-specific kinase 2 (TESK2) |
CNY 4,256.00 |
|
| RC224117L1 | Lenti-ORF clone of TESK2 (Myc-DDK-tagged)-Human testis-specific kinase 2 (TESK2) |
CNY 6,460.00 |
|
| RC224117L2 | Lenti-ORF clone of TESK2 (mGFP-tagged)-Human testis-specific kinase 2 (TESK2) |
CNY 6,460.00 |
|
| RC224117L3 | Lenti-ORF clone of TESK2 (Myc-DDK-tagged)-Human testis-specific kinase 2 (TESK2) |
CNY 6,460.00 |
|
| RC224117L4 | Lenti-ORF clone of TESK2 (mGFP-tagged)-Human testis-specific kinase 2 (TESK2) |
CNY 6,460.00 |
|
| RG224117 | TESK2 (tGFP-tagged) - Human testis-specific kinase 2 (TESK2) |
CNY 5,040.00 |
|
| SC313984 | TESK2 (untagged)-Human testis-specific kinase 2 (TESK2) |
CNY 9,220.00 |
|
| SC317980 | TESK2 (untagged)-Human testis-specific kinase 2 (TESK2) |
CNY 9,220.00 |
